Results 81 to 90 of about 32,557 (330)

Characterization of type 2 diacylglycerol acyltransferases in Chlamydomonas reinhardtii reveals their distinct substrate specificities and functions in triacylglycerol biosynthesis.

The Plant Journal, 2016
Diacylglycerol acyltransferases (DGATs) catalyze a rate-limiting step of triacylglycerol (TAG) biosynthesis in higher plants and yeast. The genome of the green alga Chlamydomonas reinhardtii has multiple genes encoding type 2 DGATs (DGTTs).
Jin Liu, Danxiang Han, Kangsup Yoon, Q. Hu, Yantao Li   +4 more
semanticscholar   +1 more source

PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species

Advanced Science, EarlyView.
Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen, Xiaoman Zhu, Michael Mingze Lu, Qingjian Ou, Xueying Wang, Zhenzhen Zhao, Qi Shen, Qian Wang, Zhe Wang, Jing‐Ying Xu, Caixia Jin, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Xiaoliang Jin, Yanlong Bi, Lixia Lu, Guo‐Tong Xu, Haibin Tian   +19 more
wiley   +1 more source

Occurrence of land-plant-specific glycerol-3-phosphate acyltransferases is essential for cuticle formation and gametophore development in Physcomitrella patens.

New Phytologist, 2019
During the evolution of land plants from aquatic to terrestrial environments, their aerial surfaces were surrounded by cuticle composed of cutin and cuticular waxes to protect them from environmental stresses.
S. Lee, S. Yang, G. Pandey, Myung-Shin Kim, Sujin Hyoung, D. Choi, J. Shin, M. Suh   +7 more
semanticscholar   +1 more source

Rekombination hybrider Megasynthasen als Schlüssel für die Evolution metabolischer Diversität in Cyanobakterien

Angewandte Chemie, EarlyView.
Natürliche Kombinatorik: Die evolutionäre Rekombination und Anpassung von drei cyanobakteriellen Biosynthese‐Genclustern führte zur Entstehung von Minutumamiden, einer neuen Familie von Peptid‐Polyketid‐Hybriden. Mittels retro‐evolutionärer Analyse gelang die Entdeckung des Nostopeptolids KVJ3, einem evolutionären Vorfahren, der die Biosynthese von ...
Keishi Ishida, Qi Sun, Jonna Teikari, Christian Hertweck, Elke Dittmann, Masahiro Murakami, Martin Baunach   +6 more
wiley   +1 more source

Recruiting a new substrate for triacylglycerol synthesis in plants: the monoacylglycerol acyltransferase pathway. [PDF]

PLoS ONE, 2012
BACKGROUND: Monoacylglycerol acyltransferases (MGATs) are predominantly associated with lipid absorption and resynthesis in the animal intestine where they catalyse the first step in the monoacylglycerol (MAG) pathway by acylating MAG to form ...
James R Petrie, Thomas Vanhercke, Pushkar Shrestha, Anna El Tahchy, Adam White, Xue-Rong Zhou, Qing Liu, Maged P Mansour, Peter D Nichols, Surinder P Singh   +9 more
doaj   +1 more source

Evolutionarily Distinct BAHD N-Acyltransferases Are Responsible for Natural Variation of Aromatic Amine Conjugates in Rice[OPEN]

The Plant Cell, 2016
Eight BAHD N-acyltransferases with diverse specificities, including four tryptamine/tyramine bifunctional N-acyltransferases, are present in the Gramineae.
Meng Peng, Yanqiang Gao, Wei Chen, Wensheng Wang, S. Shen, Jian Shi, Cheng Wang, Yu Zhang, Li Zou, Shouchuang Wang, Jian Wan, Xianqing Liu, Liang Gong, Jie Luo   +13 more
semanticscholar   +1 more source

Increased missense mutation burden of Fatty Acid metabolism related genes in nunavik inuit population. [PDF]

PLoS ONE, 2015
Nunavik Inuit (northern Quebec, Canada) reside along the arctic coastline where for generations their daily energy intake has mainly been derived from animal fat.
Sirui Zhou, Lan Xiong, Pingxing Xie, Amirthagowri Ambalavanan, Cynthia V Bourassa, Alexandre Dionne-Laporte, Dan Spiegelman, Maude Turcotte Gauthier, Edouard Henrion, Ousmane Diallo, Patrick A Dion, Guy A Rouleau   +11 more
doaj   +1 more source

Two types of soybean diacylglycerol acyltransferases are differentially involved in triacylglycerol biosynthesis and response to environmental stresses and hormones

Scientific Reports, 2016
Diacylglycerol acyltransferases (DGATs) play a key role in plant triacylglycerol (TAG) biosynthesis. Two type 1 and 2 DGATs from soybean were characterized for their functions in TAG biosynthesis and physiological roles.
Beibei Chen, Junejie Wang, Gaoyang Zhang, Jiaqi Liu, S. Manan, Honghong Hu, Jian Zhao   +6 more
semanticscholar   +1 more source

Update: Enzymatische Synthese für industrielle Anwendungen

Angewandte Chemie, EarlyView.
Die Biokatalyse hat sich zu einer nachhaltigen und wettbewerbsfähigen Alternative zur herkömmlichen chemischen Synthese entwickelt und ermöglicht die enzymbasierte Herstellung nicht nur von chemischen Grundstoffen, sondern auch von (nicht natürlichen) Aminosäuren, (seltenen) Zuckern und synthetischen Nukleotiden.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Alkyne lipids as substrates for click chemistry-based in vitro enzymatic assays

Journal of Lipid Research, 2013
Click chemistry is evolving as a powerful tool in biological applications because it allows the sensitive and specific detection of compounds with alkyne or azido groups.
Anne Gaebler, Robin Milan, Leon Straub, Dominik Hoelper, Lars Kuerschner, Christoph Thiele   +5 more
doaj