Results 171 to 180 of about 69,866 (210)

Phenotypic Effects of a Small Molecule CpxA Phosphatase Inhibitor on Uropathogenic Escherichia coli. [PDF]

ACS Infect Dis
Stoorza AM, Carlson EE, Duerfeldt AS.
europepmc   +1 more source

Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy

Allergy, EarlyView.
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider, Juan‐Felipe López, Huseyn Babayev, Willem van de Veen, Minglin Yang, Cezmi A. Akdis, Kari Nadeau, Carolyn H. Baloh, Stacie M. Jones, Lisa M. Wheatley, Mübeccel Akdis, IMPACT, Amy M. Scurlock, D. Pesek, Joy Laurienzo‐Panza, Marshall Plaut, A. Wesley Burks, Edwin H. Kim, Mike Kulis, Anna Nowak‐Wegrzyn, Hugh A. Sampson, Julie Wang, Robert A. Wood, Sharon Chinthrajah, Robert Sayantani B. Sindher, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Rachel Yan, Don Whitehouse, Michelle L. Sever, Srinath Sanda, David Larson, Tielin Qin, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien‐Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh‐Anh Nguyen, Jessica Garber, Kimberly O'Brien, Brandon Larson, C. Cousens‐Jacobs, Alex Hu   +48 more
wiley   +1 more source

Quantitative and qualitative differences in anti-Envelope IgG-secreting cells distinguish subclinical and hospitalized dengue in a Cambodian pediatric cohort. [PDF]

PLoS Pathog
Trouchet A, Lay S, Broketa M, Canales-Herrerias P, Perima A, Iannascoli B, Sann S, Heng B, Ly S, Duong V, Millot GA, Walker L, England P, Barba-Spaeth G, Cantaert T, Bruhns P.   +15 more
europepmc   +1 more source

Deep‐Learning‐Based Profiling of Mouse Sperm Head and Neck Morphology Reveals Coordinated Structural Variation

Andrology, EarlyView.
ABSTRACT Background Mammalian sperm head morphology varies across species and dictates fertilization capability. Rodent sperm have asymmetric, hook‐shaped heads, complicating analysis. Despite widespread biomedical use, current tools poorly characterize these complex variations.
Gwidong Han, Seung Pyo Hong, Seung Jae Lee, Chunghee Cho   +3 more
wiley   +1 more source

Analysis of the genome of a Pseudomonas monsensis isolate that produces the antifungal dipeptide maculosin. [PDF]

Access Microbiol
Sharma P, Kingdon ADH, Bradley JK, Allman E, Ang S, Pye M, O'Ferrall AM, McLeman A, McKeown C, Hong WD, Roberts AP.   +10 more
europepmc   +1 more source

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

British Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source

Immunometabolic Modulation in Obese Asthma: How GLP-1 Receptor Agonists Could Influence Systemic and Pulmonary Immune Phenotypes. [PDF]

Pulm Ther
O'Brien H, Byrne AJ, Franciosi AN, Butler MW.   +3 more
europepmc   +1 more source

Changes in gastrointestinal motility and gut hormone secretion after Roux‐en‐Y gastric bypass and sleeve gastrectomy for individuals with severe obesity

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink, Mark van Avesaat, Simon W. Nienhuijs, Arnold Stronkhorst, Ad A. M. Masclee   +4 more
wiley   +1 more source

Variants in CEP135 Cause Congenital Microcephaly and Primary Ciliary Dyskinesia. [PDF]

Pediatr Pulmonol
Bergman-Sieger A, Turcot MA, Ostrowski LE, Sears PR, Zariwala MA, Bechkir F, Young LR, Shapiro AJ, Parenti MB.   +8 more
europepmc   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source