Results 151 to 160 of about 2,414,840 (297)
Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, EarlyView.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
ADAM Report #22 (September 1999)
, 1999 ADAM REPORT # 22, September 1999 1. Wage Trends • Wage Increases in June '99 Quarter Certified Agreements • Wage Trends in Enterprise Agreements • Wage Increases in Current Agreements • Wage Dispersion • High Wage Agreements • Developments in Federal ...
ACIRRT; Australian Centre for Industrial Relations Research and Training
core
Solvent Effects on the Conformational Preferences of 2,6‐Pyridylcarboxamide Foldamers
Chemistry – A European Journal, EarlyView.The marked effect of organic solvents and water/methanol mixtures on the conformational preferences of a soluble chiral foldamer has been established in a diverse array of seventeen distinct environments. ABSTRACT The marked influence of organic solvents and water on the conformational preferences of a chiral, soluble 2,6‐pyridylcarboxamide foldamer ...
Alexander R. Davis +5 more
wiley +1 more source
Labeling Strategies for Monitoring Cytoskeleton Dynamics in Cultured Epithelial Cells
Cytoskeleton, EarlyView.ABSTRACT Collective cell migration relies on coordinated cytoskeletal remodeling, yet the impact of live‐cell actin filament probes on these dynamics remains poorly characterized. Here, we systematically compared the performance and cellular effects of fluorogenic jasplakinolide‐based probes, SiR‐actin and SiR‐XActin, with the genetically encoded ...
Victoria Levario‐Diaz +6 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang +2 more
wiley +1 more source
The Potential of A Disintegrin and Metalloproteinase (ADAM) Proteins as Clinically Relevant Biomarkers in Colorectal Cancer: A Comprehensive Analysis. [PDF]
Cancers (Basel)Romanowicz A +2 more
europepmc +1 more source
, 2015 ADAM REPORT # 6, August 1995 1. Features of Enterprise Agreements 2. The Narrowing of the Agenda 3.
ACIRRT
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Clinical Pharmacology &Therapeutics, EarlyView.Zavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Alice Ke +8 more
wiley +1 more source
Morphological signatures of bacteria‐laden drying droplets: A multimodal analysis across host fluids
Droplet, EarlyView.Drying patterns of bacteria‐laden droplets encode concentration‐dependent signatures across three host fluids: serum, urine, and nutrient medium. By integrating time‐evolving texture descriptors, image features, and interpretable multimodal machine learning, this study demonstrates a label‐free approach for extracting information on bacterial ...
Anusuya Pal +6 more
wiley +1 more source
Zebrafish ventral gastrula fate map reveals neural crest progenitor domain
Developmental Dynamics, EarlyView.Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley +1 more source