Results 91 to 100 of about 2,414,840 (297)

Rhenium‐Based β‐Galactosidase Probe Allows Senescence Profiling by Mass Cytometry

open access: yesAngewandte Chemie, EarlyView.
Senescence‐associated β‐galactosidase (SA‐β‐Gal) activity is a widely accepted biomarker of cellular senescence, yet its integration with other senescence markers has been limited by available detection methods. Here, we introduce ReGal, a mass cytometry‐compatible SA‐β‐Gal activity probe that can be multiplexed with established markers of senescence ...
Adam Tam   +4 more
wiley   +2 more sources

Mechanoresponsive ion channels Piezo1 and TRPV4 stimulate ADAM10 and ADAM17 with differential impact on endothelial migration and proliferation

open access: yesCell Communication and Signaling
Background Endothelial cells are constantly exposed to mechanical forces generated by blood flow regulating endothelial homeostasis. Pathological events such as vascular injury or thrombus formation alter these forces, which are sensed by endothelial ...
Alessa Pabst   +7 more
doaj   +1 more source

ADAM Report 2

open access: yes, 1994
ADAM REPORT # 2, February 1994 1. Overview of Agreements 2. Emerging Trends 3.
ACIRRT
core  

Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution

open access: yesAdvanced Science, EarlyView.
MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge   +6 more
wiley   +1 more source

In Vitro Selection of Functional Neoproteins Containing Highly Fluorinated Cores

open access: yesAngewandte Chemie, EarlyView.
The generation of neoproteins—functional proteins containing unnatural amino acids—is a key goal in synthetic biology. We develop a platform to discover neoproteins with specified bioactivity from trillion‐member sequence libraries, using genetic code reprogramming, in vitro selection and microwave peptide synthesis.
Adam Beattie   +5 more
wiley   +2 more sources

Novosadski golozrni, a spring oat variety [PDF]

open access: yesSelekcija i Semenarstvo, 2001
The naked oat variety Novosadski golozrni was developed from a cross between the variety Adam and a spring-type naked oat line from Canada. The variety is early, medium tall, with excellent resistance to lodging. The yield of Novosadski golozrni is 30-40%
Pržulj Novo   +2 more
doaj  

ADAM Report #14 (September 1997)

open access: yes, 1997
ADAM REPORT # 14, September 1997 1. Wages and Innovative Clauses 2.
ACIRRT; Australian Centre for Industrial Relations Research and Training
core  

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

open access: yesAdvanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann   +7 more
wiley   +1 more source

Hidup dan perjuangan Adam Malik

open access: yes, 1980
Buku ini membahas mengenai Hidup dan perjuangan Adam Malik. Tulisan dalam buku ini pada dasarnya membahas Perjuangan hidup Adam Malik dimulai dari bawah sehingga sukses ketempat kedudukan yang cukup tinggiViii, 317 hlm.: ilus.; 23 ...
A. Hamid Lubis   +3 more
core  

From Top to Bottom: Manufacturing Process‐Context Aware Resolution of Energy Device Electrodes Through a 3D Diffusion Generative Model

open access: yesAdvanced Energy Materials, EarlyView.
The application of a generative diffusion model, enhanced with a training data augmentation pipeline retaining the manufacturing process context of electrode microstructures, leads to improved fidelity of the through‐plane tortuosity factor in the AI generated samples.
Victor Ramirez‐Camacho   +5 more
wiley   +1 more source

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