Results 101 to 110 of about 2,414,840 (297)

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

open access: yesHepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu   +16 more
wiley   +1 more source

LRP1 shedding in human brain: roles of ADAM10 and ADAM17

open access: yesMolecular Neurodegeneration, 2009
Background The low-density lipoprotein receptor-related protein 1 (LRP1) plays critical roles in lipid metabolism, cell survival, and the clearance of amyloid-β (Aβ) peptide. Functional soluble LRP1 (sLRP1) has been detected in circulating human placenta;
Reiss Karina   +6 more
doaj   +1 more source

African rondavels, ca. 1880s [picture] /

open access: yes, 1870
Title devised by cataloguer based on information from acquisitions documentation.; Condition: "Wulmer"--In pencil below drawing.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-vn4975076; Donated by Mrs Florence ...
Forster, Adam, 1848-1928.
core  

Domain integration of ADAM family proteins: Emerging themes from structural studies

open access: yesExperimental Biology and Medicine, 2019
ADAM (a disintegrin and metalloproteinase) proteins are type-1 transmembrane and secreted proteins that function in cell adhesion and signal transduction. Here we review the structural features of ADAM proteins that direct their biological functions in ectodomain shedding and cell adhesion. Impact statement
Tom CM Seegar, Stephen C Blacklow
openaire   +3 more sources

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

John Adam Street [Adelphi development]

open access: yes
Number 8 John Adam Street (Royal Society for the Encouragement of Arts, Manufactures and Commerce), detail, medallion; Adam House (7-10 John Adam Street) is part of the Adelphi development designed in 1768-1772 by brothers Robert and John Adam.
Adam, John, Adam, Robert
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ADAM Report 1

open access: yes, 1993
ADAM REPORT # 1, October 1993 1. Basic Features of Enterprise Agreements 2. Emerging Trends 3.
ACIRRT
core  

Materials Representation Learning Based on a Material–Motif Network and Heterogeneous Graphs

open access: yesAdvanced Intelligent Discovery, EarlyView.
Structure motifs in materials are used to construct a bipartite material–motif network that links each material to its constituent motifs and establishes connectivity among materials sharing common motifs. Network analysis reveals material clusters associated with different functional applications and supports motif‐guided screening of materials.
Anoj Aryal   +3 more
wiley   +1 more source

ADAM Report #20 (March1999)

open access: yes, 1999
ADAM REPORT # 20, March 1999 1. Wage Trends • Wage Increases in December '98 Quarter Agreements • Wage Trends in Current Agreements • Wage Dispersions • High Wage Agreements • Federal AWAs • Wage Trends in AWAs 2.
ACIRRT; Australian Centre for Industrial Relations Research and Training
core  

ViTAMIn‐O: Democratizing Computer Vision‐Based Machine Learning for Stem Cell Research

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces a fully open generalist computer vision model for predicting the differentiation outcomes of stem cell‐based model systems, together with its code‐free deployment platform, ColabViTAMIn‐O. It is benchmarked against various architectures, datasets, and training protocols.
Ferhat Hamurcu   +11 more
wiley   +1 more source

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