Results 171 to 180 of about 171,066 (327)

Changes in brain white matter structure are associated with urine proteins in urologic chronic pelvic pain syndrome (UCPPS): A MAPP Network study [PDF]

, 2018
Andriole, Gerald L, Bristol, Rebecca L, Colditz, Graham, et al.,, Gardner, Vivien C, Gereau, Robert W, IV, Henderson, Jeffrey P, Hong, Barry A, Lai, H. Henry, Spitznagle, Theresa M, Sutcliffe, Siobhan   +10 more
core   +2 more sources

Quantitative susceptibility mapping in magnetically inhomogeneous tissues

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose Conventional quantitative susceptibility mapping (QSM) methods rely on simplified physical models that assume isotropic and homogeneous tissue properties, leading to artifacts and inaccuracies in biological tissues. This study aims to develop and evaluate DEEPOLE, a deep learning–based method that incorporates macroscopically ...
Thomas Jochmann, Fahad Salman, Michael G. Dwyer, Niels Bergsland, Robert Zivadinov, Jens Haueisen, Ferdinand Schweser   +6 more
wiley   +1 more source

Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK) [PDF]

, 2018
Xin Gu, Michael D. Bridges, Yan Yan, Parker W. de Waal, X. Edward Zhou, Kelly Suino-Powell, H. Eric Xu, Wayne L. Hubbell, Karsten Melcher   +8 more
openalex   +1 more source

Dietary macronutrient content and energy intake in the mouse: hedonic or homeostatic override?

Obesity, EarlyView.
Abstract Objective The objective of this study was to reconcile how two landmark mouse studies came to opposite conclusions regarding the relationship between dietary macronutrient composition and energy intake. Hu et al. concluded that dietary fat drives excess energy intake because its hedonic properties override energy homeostasis. Solon‐Biet et al.
Stephen J. Simpson, Alistair M. Senior, Samantha M. Solon‐Biet, David G. Le Couteur, David Raubenheimer   +4 more
wiley   +1 more source

ADAM Proteases in Cancer: Biological Roles, Therapeutic Challenges, and Emerging Opportunities. [PDF]

Cancers (Basel)
Arora S, Scott AM, Janes PW.
europepmc   +1 more source

Accelerating Drug Development for Neuroblastoma: Consensus Statement From the Third Neuroblastoma Drug Development Strategy Forum

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma is a poor prognosis cancer of the sympathetic nervous system that accounts for a disproportionate number of childhood cancer deaths. Many viable biological targets have been identified, and the number of potential combinations is even larger.
Steven G. DuBois, Lucas Moreno, John Anderson, Shahab Asgharzadeh, Ro Bagatell, Maja Beck‐Popovic, Jen Belle, Pablo Berlanga, Nick J. Bird, Louis Chesler, Adam Durbin, Angelika Eggert, Martin Eilers, Sara M. Federico, Matthias Fischer, Susanne A. Gatz, Rani E. George, Sally George, Kelly C. Goldsmith, Juliet Gray, Andras Heczey, Meredith S. Irwin, Leona Knox, Holger N. Lode, Donna Ludwinski, Margaret E. Macy, Robbie G. Majzner, John M. Maris, Shakeel Modak, Jan J. Molenaar, Daniel A. Morgenstern, Yael P. Mossé, Cormac Owens, C. Patrick Reynolds, Claudia Rossig, Gudrun Schleiermacher, Liz Scott, Paul M. Sondel, Frank Speleman, Max van Noesel, Frank Westermann, Judith Wienke, Adam J. Wolpaw, Julie R. Park, Andrew D. J. Pearson   +44 more
wiley   +1 more source

Current research of the Notch pathway in hepatocellular carcinoma. [PDF]

Eur J Med Res
Fu L, Gu X, Lou N, Li J, Xue C.
europepmc   +1 more source

ADAM Family Protein Mde10 Is Essential for Development of Spore Envelopes in the Fission Yeast Schizosaccharomyces pombe

, 2004
T. Nakamura, Hiroko Abe, Aiko Hirata, Chikashi Shimoda   +3 more
openalex   +1 more source

Deep learning (DL)‐based advancements in prostate cancer imaging: Artificial intelligence (AI)‐based segmentation of 68Ga‐PSMSA PET for tumor volume assessment

Precision Radiation Oncology, EarlyView.
This review highlights the use of 68Ga‐PSMA PET in prostate cancer (PC) for tumor volume quantification, crucial for staging, treatment planning, and prognosis. Traditional manual segmentation methods are time‐consuming and variable, while AI‐based segmentation techniques, particularly deep learning models like convolutional neural networks, offer ...
Sharjeel Usmani, Khulood Al Riyami, Subash Kheruka, Shah P Numani, Rashid al Sukaiti, Maria Ahmed, Nadeem Pervez   +6 more
wiley   +1 more source

Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors. [PDF]

Life Sci Alliance
Saha N, Chan E, Mendoza RP, Romin Y, Tipping MJ, Nikolov DB.   +5 more
europepmc   +1 more source