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Protein synthesis during germination of Peronospora tabacina (Adam) conidia
Archives of Biochemistry and Biophysics, 1971The characteristics of an in vitro amino acid-incorporating system prepared from germinated Peronospora tabacina conidia are described. Material sedimenting at 20,000 g and at 117,000 g was found to possess significant amino acid-incorporating activity. Although germination is accompanied by an increase in the activity of both these fractions, if
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The ADAMs family of proteins: from basic studies to potential clinical applications
Thrombosis and Haemostasis, 2003SummaryThe ADAMs are a family of membrane proteins possessing a disintegrin and metalloprotease domain. Currently,34 members are known to exist. Approximately 50% of the ADAMs contain a metalloprotease-like domain and some of these have been shown to possess protease activity.
Michael J, Duffy +3 more
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2003
Publisher Summary Since their discovery about a decade ago, some very intriguing insights into the function of a few Anchored Metalloprotease-Disintegrin Proteins (ADAMs) have emerged. They have been linked to a role in cell–cell interactions as potential integrin ligands and in the cleavage and release and, in several cases, activation of membrane ...
J David, Becherer, Carl P, Blobel
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Publisher Summary Since their discovery about a decade ago, some very intriguing insights into the function of a few Anchored Metalloprotease-Disintegrin Proteins (ADAMs) have emerged. They have been linked to a role in cell–cell interactions as potential integrin ligands and in the cleavage and release and, in several cases, activation of membrane ...
J David, Becherer, Carl P, Blobel
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ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors
American Journal of Physiology-Cell Physiology, 2006A disintegrin and metalloprotease (ADAM) is a membrane-anchored metalloprotease implicated in the ectodomain shedding of cell surface proteins, including the ligands for epidermal growth factor (EGF) receptors (EGFR)/ErbB. It has been well documented that the transactivation of the EGFR plays critical roles for many cellular functions, such as ...
Haruhiko, Ohtsu +2 more
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Induction of new adam related protein from treated human Chang-liver cells
Molecular Biology, 2010Chang-liver cells is a cell line generated from human liver tissue, which is often used in scientific research. ADAMs are a family of proteins that consist of multi-domains, possess multi-functions and play a central role in normal or abnormal physiological conditions, such as regeneration and tumorigenesis. To investigate the expression and functional
C R, Wang +5 more
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A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis
Respirology, 2012ABSTRACTBackground and objective: A disintegrin and metalloproteinase (ADAM) 33 is a susceptibility gene associated with inflammatory lung and skin diseases. It is selectively expressed in mesenchymal cells, and its metalloprotease activity has been linked to angiogenesis and tissue remodelling.
Shaffiq, Asif +8 more
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Donn Adam Gito: Exploring The Non-Classical Properties of Proteins
2023A group of proteins can generate electrical charges under applied stress, a functional property known as piezoelectricity. Although, the fundamentals of piezoelectricity are based on inorganic crystals and not on organic materials. Hence, there is ambiguity in the relationship between the structure of the proteins and their piezoelectric response.
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Activated protein C inhibits amyloid β production via promoting expression of ADAM-10
Brain Research, 2014Inhibition of Aβ production and clearance of senile plaques have been considered as potential strategies in the treatment of Alzheimer's disease (AD). Activated protein C (APC) is an important factor in the anticoagulant system. However, whether APC can influence the condition of a chronic neurodegenerative process, such as that present in AD, is ...
Bing, Li, Dawei, Yu, Zhiying, Xu
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Snake venom metalloproteinases: Structure, function and relationship to the ADAMs family of proteins
Toxicon, 1996A large number of zinc metalloproteinases of varying mol. wts and biological functions has been isolated from crotalid and viperid venoms. Over the past few years, structural studies on these proteinases have suggested their organization into four classes, P-I to P-IV.
L G, Jia +3 more
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Micron, 2006
Trophoblast fusion in the placenta is an event of major importance for the preservation of a healthy pregnancy. This process takes place throughout pregnancy and is crucial for the maintenance of the syncytiotrophoblast layer, the direct border between maternal blood and fetal tissues.
Berthold, Huppertz +2 more
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Trophoblast fusion in the placenta is an event of major importance for the preservation of a healthy pregnancy. This process takes place throughout pregnancy and is crucial for the maintenance of the syncytiotrophoblast layer, the direct border between maternal blood and fetal tissues.
Berthold, Huppertz +2 more
openaire +2 more sources