Results 51 to 60 of about 171,066 (327)
Frontiers in Cellular Neuroscience, 2015 Brain is continuously altered in response to experience and environmental changes. One of the underlying mechanisms is synaptic plasticity, which is manifested by modification of synapse structure and function.
Grzegorz eWiera +3 more
doaj +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Frontiers in Molecular Biosciences, 2021 Disintegrins are small cysteine-rich proteins found in a variety of snake venom. These proteins selectively modulate integrin function, heterodimeric receptors involved in cell-cell and cell-matrix interaction that are widely studied as therapeutic ...
Ariana A. Vasconcelos +7 more
doaj +1 more source
Role of host-derived ADAM-9 in tumor invasion and metastasis of malignant melanoma [PDF]
, 2012 A Disintegrin And Metalloproteases (ADAMs) represents a family of transmembrane proteins with a distinct multidomain structure including a metalloprotease, disintegrin, and cysteine-rich domain.
Ngum, Anna Abety
core
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2014 Matrix metalloproteinases (MMPs) are pleiotropic endopeptidases involved in a variety of neurodegenerative/neuroinflammatory processes through their interactions with a large number of substrates.
Nathalie ePy +8 more
doaj +1 more source
BMC Genomics, 2022 Background Due to the prolonged usage of Bt-based biopesticides and Bt-transgenic crops worldwide, insects are continually developing resistance against Cry toxins.
Tushar K. Dutta +6 more
doaj +1 more source
ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer
Frontiers in Cell and Developmental Biology, 2023 Introduction: Cranial neural crest (CNC) cells are induced at the border of the neural plate by a combination of FGF, Wnt, and BMP4 signaling. CNC then migrate ventrally and invade ventral structures where they contribute to craniofacial development ...
Ankit Pandey +3 more
doaj +1 more source
European Journal of Cell Biology, 2011 ADAM metalloproteases are membrane bound glycoproteins that control many biological processes during development and differentiation, mainly by acting as ectodomain sheddases. The Drosophila genome contains five genes that code for classical ADAM proteins which are characterized by a highly conserved domain structure with the respective catalytic ...
Heiko Meyer +7 more
openaire +3 more sources
ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase [PDF]
Journal of Biological Chemistry, 2009 ADAM10 is involved in the proteolytic processing and shedding of proteins such as the amyloid precursor protein (APP), cadherins, and the Notch receptors, thereby initiating the regulated intramembrane proteolysis (RIP) of these proteins. Here, we demonstrate that the sheddase ADAM10 is also subject to RIP.
Elke Maes +16 more
openaire +3 more sources