Results 271 to 280 of about 2,414,840 (297)

ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors

American Journal of Physiology-Cell Physiology, 2006
A disintegrin and metalloprotease (ADAM) is a membrane-anchored metalloprotease implicated in the ectodomain shedding of cell surface proteins, including the ligands for epidermal growth factor (EGF) receptors (EGFR)/ErbB. It has been well documented that the transactivation of the EGFR plays critical roles for many cellular functions, such as ...
Haruhiko, Ohtsu, Peter J, Dempsey, Satoru, Eguchi   +2 more
openaire   +2 more sources

Biochemical properties and functions of membrane-anchored metalloprotease-disintegrin proteins (ADAMs)

2003
Publisher Summary Since their discovery about a decade ago, some very intriguing insights into the function of a few Anchored Metalloprotease-Disintegrin Proteins (ADAMs) have emerged. They have been linked to a role in cell–cell interactions as potential integrin ligands and in the cleavage and release and, in several cases, activation of membrane ...
J David, Becherer, Carl P, Blobel
openaire   +2 more sources

Functional and biochemical characterization of ADAMs and their predicted role in protein ectodomain shedding

Inflammation Research, 2002
Proteolysis on the cell surface and in the extracellular matrix is essential for normal cellular functions during development and in the adult, but it may also have undesirable consequences by promoting diseases such as cancer, arthritis, and Alzheimer's disease.
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Donn Adam Gito: Exploring The Non-Classical Properties of Proteins

2023
A group of proteins can generate electrical charges under applied stress, a functional property known as piezoelectricity. Although, the fundamentals of piezoelectricity are based on inorganic crystals and not on organic materials. Hence, there is ambiguity in the relationship between the structure of the proteins and their piezoelectric response.
openaire   +1 more source

Role for ADAM-family proteinases as membrane protein secretases

Biochemical Society Transactions, 1999
A J, Turner, N M, Hooper
openaire   +2 more sources

A role for ADAMs proteinases as membrane protein secretases

Biochemical Society Transactions, 1999
Anthony J. Turner, Nigel M. Hooper
openaire   +1 more source

ADAM Family Protein

2020
openaire   +1 more source

Quantitative and dynamic expression profile of premature and active forms of the regional ADAM proteins during chicken brain development

Cellular and Molecular Biology Letters, 2011
Jiankai Luo
exaly  

The evolution of ADAM gene family in eukaryotes

Genomics, 2020
Rui Oliveira
exaly  

metalloproteases in development and differentiation: The role of ADAM proteins and their relatives

European Journal of Cell Biology, 2011
Heiko Meyer, Shuoshuo Wang, Achim Paululat   +2 more
exaly