Results 191 to 200 of about 69,298 (248)

Early onset rapidly progressive frontotemporal dementia due to a novel MAPT P301A variant with functional validation of pathogenicity. [PDF]

NPJ Dement
Hua K, Pearson MR, Apresa BI, Chung JM, Ambrose AJ, Hiatt SM, Lario Lago A, Hall MG, Rabkina L, Kwan S, Do J, Daghlas I, McDonough A, Guterman EL, Xu DJ, Rosen HJ, Grimwood J, Cochran JN, Arkin MR, Boxer AL, Yokoyama JS, Ljubenkov PA, Holmes BB.   +22 more
europepmc   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

Insect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo, João Alfredo Teodoro, Danilo T. Amaral   +2 more
wiley   +1 more source

Metabolic Imaging and Molecular Signatures Reveal Metabolic Phenotypes in Recurrent Glioblastoma. [PDF]

J Nucl Med
Li EJ, Kraya A, Costa-Pinheiro P, Scheuermann J, Young AJ, Schubert E, Aboian M, Doot R, Ware JB, Pantel AR, Binder ZA, Storm PB, Resnick AC, Amankulor NM, O'Rourke DM, Desai A, Nasrallah MP, Brem S, Bagley SJ, Mankoff D, Nabavizadeh A.   +20 more
europepmc   +1 more source

Melanoma and Other Melanistic Lesions in Brown Bullhead Ameiurus nebulosus From Waterbodies in the Northeastern United States and Canada: Identification of Risk Factors

Journal of Fish Diseases, EarlyView.
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer, Peter Emerson, Matthew Bodnar, Thomas Jones, David R. Russell, Matthew Pehrson, Cheyenne R. Smith, Danielle Cleveland, Mark J. Henderson, Patricia M. Mazik   +9 more
wiley   +1 more source

Corrigendum to "Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation" [Mol Metab 18 (2018) 153-163]. [PDF]

Mol Metab
Gupta MK, De Jesus DF, Kahraman S, Valdez IA, Shamsi F, Yi L, Swensen AC, Tseng YH, Qian WJ, Kulkarni RN.   +9 more
europepmc   +1 more source

3SD: Rotational symmetry single‐shot denoising in fluorescence microscopy

Journal of Microscopy, EarlyView.
Abstract Image noise is a fundamental problem in fluorescence microscopy analysis, especially in live cell imaging applications where the number of detected photons is limited due to low power of excitation lasers to prevent phototoxicity during extended imaging experiments.
Tijmen H. de Wolf, Pleun Engbers, Justine Perrin, Julie Nonnekens, Ihor Smal   +4 more
wiley   +1 more source

<i>In vitro</i> assays to monitor membrane fusion. [PDF]

Front Cell Dev Biol
Madison HJ, Yokom AL.
europepmc   +1 more source

Evaluating integrative strategies for incorporating phenotypic features in spatial transcriptomics

Journal of Microscopy, EarlyView.
Abstract The key advantage of spatial transcriptomics (ST) technologies lies in the spatial domain: these techniques not only offer an unprecedented opportunity to interrogate intact biological samples in a spatially informed manner, but also set the stage for integration with other imaging‐based modalities.
Levin M Moser, Ahmad Kamal Hamid, Esteban Miglietta, Nodar Gogoberidze, Beth A Cimini   +4 more
wiley   +1 more source

Identification and validation of genes encoding humoral specificity for the chemical allergen toluene diisocyanate. [PDF]

PLoS One
Wisnewski AV, Liu J.
europepmc   +1 more source