Results 31 to 40 of about 12,483 (230)

Mannose-decorated cyclodextrin vesicles: The interplay of multivalency and surface density in lectin–carbohydrate recognition

Beilstein Journal of Organic Chemistry, 2012
Cyclodextrin vesicles are versatile models for biological cell membranes since they provide a bilayer membrane that can easily be modified by host–guest interactions with functional guest molecules.
Ulrike Kauscher, Bart Jan Ravoo
doaj   +1 more source

Lipidation of NOD2 Agonists with Adamantane and Stearoyl Moieties Differentially Regulates Their In Vivo Adjuvant Activity

Pharmaceutics, 2022
NOD2 is an innate immune receptor that constitutes an important target for the development of small molecule immunopotentiators with great potential to be used as vaccine adjuvants.
Samo Guzelj, Marcela Šišić, Špela Bizjak, Leo Frkanec, Ruža Frkanec, Žiga Jakopin   +5 more
doaj   +1 more source

Novel Biphenyl Amines Inhibit Oestrogen Receptor (ER)-α in ER-Positive Mammary Carcinoma Cells

Molecules, 2021
Herein, the activity of adamantanyl-tethered-biphenyl amines (ATBAs) as oestrogen receptor alpha (ERα) modulating ligands is reported. Using an ERα competitor assay it was demonstrated that ATBA compound 3-(adamantan-1-yl)-4-methoxy-N-(4-(trifluoromethyl)
Basappa Basappa, Baburajeev Chumadathil Pookunoth, Mamatha Shinduvalli Kempasiddegowda, Rangappa Knchugarakoppal Subbegowda, Peter E. Lobie, Vijay Pandey   +5 more
doaj   +1 more source

Adamantane-Resistant Influenza Infection During the 2004–05 Season

Emerging Infectious Diseases, 2008
Adamantane-resistant influenza A is an emerging problem, but infections caused by resistant and susceptible viruses have not been compared. We identified adamantane resistance in 47% of 152 influenza A virus (H3N2) isolates collected during 2005 ...
Mahbubur Rahman, Rick A. Bright, Burney A. Kieke, James G. Donahue, Robert T. Greenlee, Mary Vandermause, Amanda Balish, Angela Foust, Nancy J. Cox, Alexander I. Klimov, David K. Shay, Edward A. Belongia   +11 more
doaj   +1 more source

Synthesis of Norabietyl and Nordehydroabietyl Imidazolidine-2,4,5-Triones and Their Activity against Tyrosyl-DNA Phosphodiesterase 1

Molbank, 2023
New imidazolidine-2,4,5-triones with norabietic, nordehydroabietic, and adamantane substituents were synthesized by reacting oxalyl chloride and the corresponding ureas, providing good yields. Bioisosteric replacement of the ureide group with a parabanic
Kseniya S. Kovaleva, Olga I. Yarovaya, Irina A. Chernyshova, Alexandra L. Zakharenko, Sergey V. Cheresiz, Amirhossein Azimirad, Andrey G. Pokrovsky, Olga I. Lavrik, Nariman F. Salakhutdinov   +8 more
doaj   +1 more source

X-ray Structures and Computational Studies of Two Bioactive 2-(Adamantane-1-carbonyl)-N-substituted Hydrazine-1-carbothioamides

Molecules, 2022
Two biologically active adamantane-linked hydrazine-1-carbothioamide derivatives, namely 2-(adamantane-1-carbonyl)-N-(tert-butyl)hydrazine-1-carbothioamide) 1 and 2-(adamantane-1-carbonyl)-N-cyclohexylhydrazine-1-carbothioamide 2, have been synthesized ...
Lamya H. Al-Wahaibi, Kowsalya Alagappan, Olivier Blacque, Ahmed A. B. Mohamed, Hanan M. Hassan, María Judith Percino, Ali A. El-Emam, Subbiah Thamotharan   +7 more
doaj   +1 more source

Adamantane-Based Crystals with Rhythmic Morphologies

, 2016
Fibrous morphologies were obtained from two tetrasubstituted adamantanes. One fiber consisted of crystals having aspect ratios of 2−3 orders of magnitude.
Vasily A. Migulin (842506), Fredric M. Menger (2225380)   +1 more
core   +1 more source

Dispersion‐Clamped Crystalline Supramolecular Columnar π‐Stacks of Adamantyl‐Substituted Pyrenes

Angewandte Chemie, EarlyView.
Can neutral hydrocarbon π‐systems be forced into perfectly aligned cofacial stacks in crystals? An adamantyl‐decorated pyrene derivative crystallizes into rare translationally zero‐offset π‐columns, producing a short π–π distance below 3.3 Å and a large color shift arising from frontier crystal orbital (FCO) formation. ABSTRACT Despite their importance
Kazutaka Shoyama
wiley   +2 more sources

Bis(μ4-adamantane-1,3-dicarboxylato-1κO1:2κO1′:3κO3:4κO3′)octacarbonyl-1κ2C,2κ2C,3κ2C,4κ2C-tetrakis[tris(4-methylphenyl)phosphane]-1κP,2κP,3κP,4κP-tetraosmium(I)(2 Os–Os)

IUCrData, 2020
The title complex, [{Os2(CO)4(C21H21P)2}2(C12H14O4)2], is a centrosymmetric molecular loop consisting of two Os—Os sawhorse units linked by two adamantane dicarboxylato bridges.
Diego F. Zometa Paniagua, Gregory L. Powell, Cynthia B. Powell, Eric W. Reinheimer   +3 more
doaj   +1 more source

Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition

Angewandte Chemie, EarlyView.
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando, Laora Boulo, Léonid Lavnevich, Elisa Teyssou, Stéphane Marot, Adélie Gothland, Jean‐Michel Guigner, Anne‐Geneviève Marcelin, Mickaël Ménand, Vincent Calvez, Matthieu Sollogoub   +10 more
wiley   +2 more sources