Results 31 to 40 of about 11,524 (228)

The Structure of Adamantane Clusters: Atomistic vs. Coarse-Grained Predictions From Global Optimization

Frontiers in Chemistry, 2019
Candidate structures for the global minima of adamantane clusters, (C10H16)N, are presented. Based on a rigid model for individual molecules with atom-atom pairwise interactions that include Lennard-Jones and Coulomb contributions, low-energy structures ...
Javier Hernández-Rojas, Florent Calvo
doaj   +1 more source

Bioactive Molecules – Polycyclic Guanidine Derivatives [PDF]

Kemija u Industriji, 2015
Biological activity of different adamantane derivatives and their application has been described in various reviews. Similarly, many reviews deal with biological activity and application of guanidine compounds.
M. Šekutor , K. Mlinarić-Majerski
doaj   +1 more source

4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer’s Disease

Pharmaceutics, 2022
Considering that acetylcholinesterase (AChE) inhibition is the most important mode of action expected of a potential drug used for the treatment of symptoms of Alzheimer’s disease (AD), our previous pilot study of 4-aminoquinolines as potential human ...
Katarina Komatović, Ana Matošević, Nataša Terzić-Jovanović, Suzana Žunec, Sandra Šegan, Mario Zlatović, Nikola Maraković, Anita Bosak, Dejan M. Opsenica   +8 more
doaj   +1 more source

Adamantane ionic liquids [PDF]

, 2014
Accepted 11 Jun 2014.We report the synthesis and characteristic thermal properties of the adamantane-based ionic salts. The ionic salts with adamantane carboxylates and imidazolium cations were prepared via neutralization.
Hiraoka, Tatsuhiro, Chujo, Yoshiki, Tanaka, Kazuo, Ishiguro, Fumiyasu, Jeon, Jong-Hwan   +4 more
core   +1 more source

Lipidation of NOD2 Agonists with Adamantane and Stearoyl Moieties Differentially Regulates Their In Vivo Adjuvant Activity

Pharmaceutics, 2022
NOD2 is an innate immune receptor that constitutes an important target for the development of small molecule immunopotentiators with great potential to be used as vaccine adjuvants.
Samo Guzelj, Marcela Šišić, Špela Bizjak, Leo Frkanec, Ruža Frkanec, Žiga Jakopin   +5 more
doaj   +1 more source

Mannose-decorated cyclodextrin vesicles: The interplay of multivalency and surface density in lectin–carbohydrate recognition

Beilstein Journal of Organic Chemistry, 2012
Cyclodextrin vesicles are versatile models for biological cell membranes since they provide a bilayer membrane that can easily be modified by host–guest interactions with functional guest molecules.
Ulrike Kauscher, Bart Jan Ravoo
doaj   +1 more source

Synthesis of Adamantane Derivatives. III. Synthesis of Adamantane Heterocycles [PDF]

Bulletin of the Chemical Society of Japan, 1969
Abstract Preparation of 1-adamantyl and adamantane-1-carbonyl derivatives having benzimidazole, 1,3,5-oxadiazole, oxazoline-2, quinoxaline, 2-aminothiazole, thiazolone, 2-methylthiazole, 1,2,3-thiadiazole, pyrazole or pyrazoline ring is described.
Tadashi Sasaki, Shoji Eguchi, Takeshi Toru   +2 more
openaire   +1 more source

Novel Biphenyl Amines Inhibit Oestrogen Receptor (ER)-α in ER-Positive Mammary Carcinoma Cells

Molecules, 2021
Herein, the activity of adamantanyl-tethered-biphenyl amines (ATBAs) as oestrogen receptor alpha (ERα) modulating ligands is reported. Using an ERα competitor assay it was demonstrated that ATBA compound 3-(adamantan-1-yl)-4-methoxy-N-(4-(trifluoromethyl)
Basappa Basappa, Baburajeev Chumadathil Pookunoth, Mamatha Shinduvalli Kempasiddegowda, Rangappa Knchugarakoppal Subbegowda, Peter E. Lobie, Vijay Pandey   +5 more
doaj   +1 more source

Synthesis of Norabietyl and Nordehydroabietyl Imidazolidine-2,4,5-Triones and Their Activity against Tyrosyl-DNA Phosphodiesterase 1

Molbank, 2023
New imidazolidine-2,4,5-triones with norabietic, nordehydroabietic, and adamantane substituents were synthesized by reacting oxalyl chloride and the corresponding ureas, providing good yields. Bioisosteric replacement of the ureide group with a parabanic
Kseniya S. Kovaleva, Olga I. Yarovaya, Irina A. Chernyshova, Alexandra L. Zakharenko, Sergey V. Cheresiz, Amirhossein Azimirad, Andrey G. Pokrovsky, Olga I. Lavrik, Nariman F. Salakhutdinov   +8 more
doaj   +1 more source

1-(2-Phenylethyl)adamantane [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
In the title compound, C(18)H(24), the adamantane cage consists of three fused cyclo-hexane rings in almost ideal chair conformations, with C-C-C angles in the range 108.0 (14)-111.1 (15)°. The phenyl and 1-adamantyl substituents adopt anti orientations with a C-C-C-C torsion angle of 177.10 (16)°.
Rouchal, Michal, Nečas, Marek, Vícha, Robert   +2 more
openaire   +4 more sources