Results 131 to 140 of about 2,929,035 (154)

A cardiac transcriptional enhancer is repurposed during regeneration to activate an anti-proliferative program.

open access: yesDevelopment
Rao A   +10 more
europepmc   +1 more source

Over-expression of Adamts1 in mice alters bone mineral density

open access: yesJournal of Bone and Mineral Metabolism, 2011
ADAMTS1, a secreted multifunctional metalloproteinase with disintegrin and thrombospondin motifs, is an early response gene of parathyroid hormone (PTH) in osteoblasts.
Håkan Melhus   +2 more
exaly   +2 more sources
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Secreted protein acidic and rich in cysteine (SPARC) and a disintegrin and metalloproteinase with thrombospondin type 1 motif (ADAMTS1) increments by the renin-angiotensin system induce renal fibrosis in deoxycorticosterone acetate-salt hypertensive rats

European Journal of Pharmacology, 2022
Secreted protein acidic and rich in cysteine (SPARC), an extracellular matrix (ECM) protein, was recently shown to induce collagen deposition through the production of a disintegrin and metalloproteinase with thrombospondin type 1 motif (ADAMTS1) in the aging heart.
Hiroe Toba   +3 more
openaire   +2 more sources

HDAC inhibition upregulates the expression of angiostatic ADAMTS1 [PDF]

open access: yesFEBS Letters, 2008
HDAC inhibitors are promising anticancer agents that induce cell cycle arrest and apoptosis. However, the role of HDACs in cancer progression, such as angiogenesis and metastasis, remains largely unexplored.
Ching-Chow Chen
exaly   +2 more sources

Adamts1 is highly induced in rachitic bones of FGF23 transgenic mice and participates in degradation of non-mineralized bone matrix collagen

open access: yesBiochemical and Biophysical Research Communications, 2013
Transgenic mice overexpressing fibroblast growth factor 23 (FGF23) in osteoblasts have a rachitic bone phenotype. These mice display hypomineralized bones, increased expression of osteoblast markers, but osteoclast numbers are unaltered or slightly ...
Håkan Melhus, Thomas Lind
exaly   +2 more sources

The Role of ADAMTS1 and Versican in Human Myocardial Infarction: A Postmortem Study

open access: yesLaboratory Medicine, 2016
Objective: To determine the role of a disintegrin and metalloproteinase with thrombospondin type 1 motif (ADAMTS1) and fragmented versican in the myocardial infarction (MI) process in humans and to evaluate the diagnostic efficacy of ADAMTS1 for ...
Ömer Akyol   +2 more
exaly   +2 more sources

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