Results 61 to 70 of about 1,276,486 (299)

Sexual behavior in male mice is impaired by an obesogenic-diabetogenic diet and worsened by exposure to a relevant environmental mixture of phthalates

open access: yesEnvironment International
The decrease in male fertility observed since the beginning of the 20th century in Western countries could be linked to changes in diets and exposure to molecules from industry, such as endocrine disruptors and, among them, phthalates.
Mahiddine Lina   +5 more
doaj   +1 more source

Limited use of transformative adaptation in response to social-ecological shifts driven by climate change [PDF]

open access: gold, 2020
Giacomo Fedele   +4 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Influence of Neuromuscular Activity and Technical Determinants on Scull Rowing Performance

open access: yesApplied Sciences
Rowing is a complex sport where technique can significantly impact performance. A better understanding of the rowers’ technique and neuromuscular activations during scull rowing, along with their impact on rowing performance, could greatly help trainers ...
Lorenzo Pitto   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Adaptive planning [PDF]

open access: yesCognitive Science, 1988
Adaptive Planning is an approach to planning in the commonsense domain. An adaptive planner takes advantage of the habitual nature of many of the planning situations for which it plans by bosing its activities on a memory of pre‐stored plans. A critical issue, and the subject of this paper, is the question of flexibility: How does an adaptive planner ...
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Estimation of Forces and Powers in Ergometer and Scull Rowing Based on Long Short-Term Memory Neural Networks

open access: yesSensors
Analyzing performance in rowing, e.g., analyzing force and power output profiles produced either on ergometer or on boat, is a priority for trainers and athletes.
Lorenzo Pitto   +4 more
doaj   +1 more source

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