Results 61 to 70 of about 2,154,051 (288)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Influencing adaptation processes on the Australian rangelands for social and ecological resilience

open access: yesEcology and Society, 2014
Resource users require the capacity to cope and adapt to climate changes affecting resource condition if they, and their industries, are to remain viable.
Nadine A. Marshall, Chris J. Stokes
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

How Adaptive Is an Adaptive Test: Are All Adaptive Tests Adaptive?

open access: yesJournal of Computerized Adaptive Testing, 2019
The primary distinguishing feature of computerized adaptive testing (CAT) is that sets of items that are administered to examinees are specifically selected for each examinee during the test process. This implies that examinees who respond differently to items on a test will get different sets of test items.
Mark Reckase, Unhee Ju, Sewon Kim
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Impact of proximity definitions and sampling rates on social networks in pigs based on tracking using computer vision

open access: yesScientific Reports
In farm animals, social network analysis has become a popular approach to explore preferential associations. This study investigated how different spatial proximity definitions and sampling rates affect social networks based on proximity using computer ...
Clémence A. E. M. Orsini   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

On the issue of the safety of the developing subject-spatial environment of a preschool educational organization

open access: yesПсихологическая наука и образование
Context and relevance. Developing the subject-spatial environment (RPPS) as one of the components of the educational environment should be safe for students. However, the safety requirements concern only the preservation of children's life and
M.Y. Paramonova   +3 more
doaj   +1 more source

Genomic preselection with genotyping-by-sequencing increases performance of commercial oil palm hybrid crosses

open access: yesBMC Genomics, 2017
Background There is great potential for the genetic improvement of oil palm yield. Traditional progeny tests allow accurate selection but limit the number of individuals evaluated. Genomic selection (GS) could overcome this constraint.
David Cros   +10 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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