Results 71 to 80 of about 5,193,405 (369)

What are the effects of climate variability and change on ungulate life-histories, population dynamics, and migration in North America? A systematic map protocol

open access: yesEnvironmental Evidence, 2020
Background Climate is an important driver of ungulate life-histories, population dynamics, and migratory behaviors, and can affect the growth, development, fecundity, dispersal, and demographic trends of populations.
Katherine C. Malpeli   +3 more
doaj   +1 more source

CMA-ES with Two-Point Step-Size Adaptation [PDF]

open access: yes, 2008
We combine a refined version of two-point step-size adaptation with the covariance matrix adaptation evolution strategy (CMA-ES). Additionally, we suggest polished formulae for the learning rate of the covariance matrix and the recombination weights.
Hansen, Nikolaus
core   +3 more sources

Regional development and climate change adaptation: a study of the role of legitimacy [PDF]

open access: yes, 2016
This paper presents results from a study of Czech Local Action Groups (LAGs), focusing on gaining knowledge about their internally perceived legitimacy and their potential role in local adaptation to climate change.
Danihelka, Pavel   +4 more
core   +2 more sources

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

A snow and ice melt seasonal prediction modelling system for Alpine reservoirs [PDF]

open access: yesProceedings of the International Association of Hydrological Sciences, 2016
The timing and the volume of snow and ice melt in Alpine catchments are crucial for management operations of reservoirs and hydropower generation. Moreover, a sustainable reservoir operation through reservoir storage and flow control as part of flood ...
K. Förster   +8 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Exposome variations affect Drosophila bristle patterning via the regulation of proneural genes through distinct mechanisms

open access: yesScientific Reports
How developing organisms respond to a changing environment is a fundamental question. Pollutants and temperature are major environmental factors.
Valérie Ribeiro   +4 more
doaj   +1 more source

Quelques caractéristiques des races bovines allaitantes de type rustique

open access: yesINRAE Productions Animales, 1994
Les bovins des races rustiques allaitantes ont des caractéristiques physiologiques qui leur permettent de s’adapter à des conditions difficiles et d’y maintenir assez bien leurs productions.
M. PETIT   +3 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

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