Results 131 to 140 of about 7,757,834 (351)

Impact of Sensory Adapted Dental Environment on Children with Developmental Disabilities [PDF]

, 2018
Purpose: This was a pilot study assessing the impact of a sensory adapted dental environment (SADE) on children with developmental disabilities (DD) receiving routine dental care.
Kim, Gail
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Identifying Ocean Submesoscale Activity From Vertical Density Profiles Using Machine Learning

Earth and Space Science
Submesoscale eddies are important features in the upper ocean where they mediate air‐sea exchanges, convey heat and tracer fluxes into ocean interior, and enhance biological production.
Leyu Yao, John R. Taylor, Dani C. Jones, Scott D. Bachman   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

New views on the emission and structure of the solar transition region

, 2010
The Sun is the only star that we can spatially resolve and it can be regarded as a fundamental plasma laboratory of astrophysics. The solar transition region (TR), the layer between the solar chromosphere and corona, plays an important role in solar wind
Aiouaz, Aiouaz, Athay, Athay, Axford, Bartoe, Bartoe, Bartoe, Basri, Bocchialini, Bohlin, Bonnet, Brekke, Brosius, Brosius, Brosius, Brown, Brueckner, Brueckner, Brueckner, Brynildsen, Büchner, Büchner, Chae, Chae, Chae, Chen, Chen, Chen, Chuanyi Tu, Culhane, Curdt, Curdt, Curdt, Curdt, Curdt, Curdt, Dammasch, Dammasch, De Pontieu, Del Zanna, Dere, Dere, Dere, Doschek, Doschek, Doschek, Dowdy, Doyle, Doyle, Doyle, Doyle, Eckart Marsch, Evershed, Evershed, Falconer, Fang, Feldman, Feldman, Feldman, Fontenla, Fontenla, Foukal, Foukal, Foukal, Gabriel, Golub, Gontikakis, Gouttebroze, Gouttebroze, Griffiths, Gunár, Guo, Habbal, Hansteen, Hansteen, Harra, Harrison, Harrison, Hassler, He, He, He, Heinzel, Hui Tian, Hénoux, Ichimoto, Imada, Innes, Innes, Jiansen He, Jin, Jordan, Katsukawa, Kneer, Lemaire, Lemaire, Lemaire, Li, Liu, Longcope, Madjarska, Madjarska, Magara, Mariska, Mariska, Marsch, Marsch, Marsch, Marsch, Marsch, Marsch, McClymont, McIntosh, McIntosh, McIntosh, McIntosh, Metcalf, Nicolas, Nicolas, Parnell, Patsourakos, Peter, Peter, Peter, Peter, Peter, Popescu, Priest, Raju, Ravindra, Reeves, Sakao, Santos, Schmieder, Schrijver, Seehafer, Sheeley, Solanki, Stucki, Teriaca, Teriaca, Teriaca, Teriaca, Teriaca, Teriaca, Tian, Tian, Tian, Tian, Tian, Tian, Tian, Tian, Tian, Tian, Tian, Tian, Tu, Tu, Tu, Ugarte-Urra, Ugarte-Urra, Ugarte-Urra, Vernazza, Vernazza, Vial, Vial, Vial, Wang, Wang, Warren, Watanabe, Webb, Werner Curdt, Wiegelmann, Wiegelmann, Wiegelmann, Wilhelm, Wilhelm, Wilhelm, Wilhelm, Wilhelm, Xia, Xia, Xia, Xu, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang   +192 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Safety and Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in Individuals ≥12 Years Old: A Phase 2/3 Trial

Vaccines
Vaccination remains an important mitigation tool against COVID-19. We report 1-month safety and preliminary immunogenicity data from a substudy of an ongoing, open-label, phase 2/3 study of monovalent Omicron XBB.1.5-adapted BNT162b2 (single 30-μg dose).
Juleen Gayed, Oyeniyi Diya, Francine S. Lowry, Xia Xu, Vishva Bangad, Federico Mensa, Jing Zou, Xuping Xie, Yanping Hu, Claire Lu, Mark Cutler, Todd Belanger, David Cooper, Kenneth Koury, Annaliesa S. Anderson, Özlem Türeci, Uǧur Şahin, Kena A. Swanson, Kayvon Modjarrad, Alejandra Gurtman, Nicholas Kitchin   +20 more
doaj   +1 more source

Analysis of activity of health workers in educational organizations and needs for medical care of children with disabilities [PDF]

Саратовский научно-медицинский журнал, 2017
Objective: study of the current state of medical support for children in educational organizations and an assessment of the needs of children with disabilities in medical care. Material and Methods.
Fomina A.V., Grigorieva N.A., Shovkun N.V.   +2 more
doaj