Results 61 to 70 of about 423,044 (308)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Gender Participation and Performance in Boccia International-Level Events

Journal of Functional Morphology and Kinesiology
Background/Objectives: Boccia is an attractive and growing adapted sport. For approximately 30 years, this parasport was played together by male and female athletes, a fact that recently changed, to our best knowledge, without scientific support.
Cátia C. Ferreira, José M. Gamonales, Jesús Muñoz-Jiménez, Mário C. Espada   +3 more
doaj   +1 more source

Exercise-induced tendon and bone injury in recreational runners: A test-retest reliability study [PDF]

, 2015
Background: Long-distance runners are prone to injuries including Achilles tendinopathy and medial tibial stress syndrome. We have developed an Internet comprehensive self-report questionnaire examining the medical history, injury history, and running ...
Compton, Stacey, Domaschenz, Renae, Hughes, David, Keogh, Justin W L, Vlahovich, Nicole   +4 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Validity and Reliability of Inertial Motion Unit-Based Performance Metrics During Wheelchair Racing Propulsion

Sensors
This study aims to evaluate the concurrent validity and test–retest reliability of wheelchair racing performance metrics. Thirteen individuals without disabilities and experience in wheelchair racing were evaluated twice while performing maximal efforts ...
Raphaël Ouellet, Katia Turcot, Nathalie Séguin, Alexandre Campeau-Lecour, Jason Bouffard   +4 more
doaj   +1 more source

Self-perception and perception of leadership behaviours of Special Olympics Portugal coaches

E-balonmano.com: Revista de Ciencias del Deporte, 2022
Coaches have a fundamental role in the holistic development of their athletes, and when we talk about adapted sports, this prerogative gains more relevance, since sports are a transforming vehicle in the athletes' lives.
Pedro Pires, Marco Batista, Helena Mesquita, Sergio J. Ibáñez   +3 more
doaj  

Effects of accuracy training for individuals with various disabilities in inclusive game Baskin [PDF]

Specijalna Edukacija i Rehabilitacija
Numerous studies have indicated the positive effects of adapted sports programs on enhancing the sports skills of individuals with multiple forms of disabilities. Aim. The aim of this research was to examine the extent of changes over four time series in
Milošević Živan N.
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The General Motor Ability Hypothesis: An old idea revisited [PDF]

, 2018
While specific motor abilities have become a popular explanation for motor performance, the older, alternate notion of a general motor ability should be revisited.
Hands, Beth, McIntyre, Fleur, Parker, Helen   +2 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source