Results 71 to 80 of about 423,044 (308)

CAREER LONGEVITY OF ELITE LATVIAN ATHLETES [PDF]

open access: yesJournal of Applied Sports Sciences
In recent years, sports psychology researchers have shown a growing interest in exploring various facets of sports careers, career transitions, the personal qualities profile of athletes who achieve peak sports performance, and the existing models and ...
Dace Eikena, Tatiana Iancheva
doaj   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

De-sportizing physical activity: From sport-for-development to play-for-development [PDF]

open access: yes, 2015
Although many initiatives use sport as a tool to blur boundaries and foster social mixing, the way physical activity is organised and displayed for such purposes suggests critical refl ections about the potential of sport in terms of social inclusivity ...
Sterchele, D
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

CONTRIBUTION OF SPORTS ADAPT TO LABOUR MARKET INSERTION OF PEOPLE WITH DISABILITIES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2013
People with different types of disabilities, still face significant barriers and prejudices that lead to thefailure of their rights and in terms of labour market access is difficult due to the fact that these people do not receiveenough support in their ...
DURBĂCEA-BOLOVAN MARIAN
doaj  

Some comparative economics of the organization of sports: competition and regulation in north American vs. European professional team sports leagues [PDF]

open access: yes
This article contends that a new research avenue is open to comparative economics which is the economic comparison between American (closed) and European (open) professional team sports leagues.
Wladimir Andreff
core  

Comparison of lower body segment alignment of elite level hockey players to age-matched non-hockey players [PDF]

open access: yes, 2015
Master's Project (M.A.) University of Alaska Fairbanks, 2015Lower body overuse and insidious onset injuries are thought to have an underlying biomechanical component which may be predisposing to injury. The purpose of this study was to compare lower body
Kimbal, Jim R.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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