Results 111 to 120 of about 2,348,191 (254)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Correlated Photon Lidar Based on Time-Division Multiplexing
PhotonicsSingle-photon lidar (SPL) exhibits high sensitivity, making it particularly suitable for detecting weak echoes over long distances. However, its susceptibility to background noise necessitates the implementation of advanced filtering techniques and ...
Yun Jiang +8 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Analogue Adaptive Filters Using Wave Synthesis Technique
, 2004 This paper describes new analogue adaptive filters based on wave synthesis technique. To facilitate simple adaptation process and stability checks, adaptive series and parallel wave adaptors with only one variable coefficient are developed including a ...
Xie, Yan, Al-Hashimi, Bashir
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
An unconventional adaptive flutter suppression actuation system: From modeling to experimentation
, 2015 This paper contributes to the definition of an unconventional actuation system, intended specifically for slender/highly flexible wings' flutter suppression, and coupled with an adaptive control algorithm to handle post-flutter flight dynamics and ...
Gili P. +3 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
An Agent-Based Framework to Support Adaptive Hypermedia
, 2002 The field of adaptive hypermedia is a little over a decade old. It has a rich history in a range of fields such as artificial intelligence, user modelling, intelligent tutoring systems and hypertext.
Bailey, Christopher P. +1 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Vibration control of MRE isolator-embedded smart building using genetic algorithm
, 2019 This study developed the adaptive genetic algorithm (GA) for vibration control of building structures subjected to ambient hazard excitations. An innovative smart building system was designed based on magnetorheological elastomer (MRE) isolators under ...
Li, Yancheng +5 more
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