Results 141 to 150 of about 648,356 (307)

Improved broadband adaptive beamformer performance

The protection of wireless communications links against interference is a key concern in mission critical systems. In particular low probability of interception (LPI) systems which operate below the thermal noise floor of the receiver are particularly ...
Tisdale, Neil
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Long-term student performance prediction using learning ability self-adaptive algorithm

Complex & Intelligent Systems
Predicting student performance is crucial for both preventing failure and enabling personalized teaching-and-learning strategies. The digitalization of educational institutions has led to the collection of extensive student learning data over the years ...
Yi Ren, Xinjie Yu
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Abstract INCORPORATING COGNITIVE STYLES IN AHA!

, 2008
Adaptive educational hypermedia environments use properties of the application domain (e.g. conceptual structure of a course, with prerequisite relationships) to perform adaptation based on the user’s browsing behaviour.
The Adaptive Hypermedia Architecture
core  

Some properties of a Bayesian adaptive ability testing strategy

, 1977
Four monte carlo simulation studies of Owen’s Bayesian sequential procedure for adaptive mental testing were conducted. In contrast to previous simulation studies of this procedure which have concentrated on evaluating it in terms of the correlation
McBride, James R.
core   +1 more source

Enhancing Ability Estimation with Time-Sensitive IRT Models in Computerized Adaptive Testing

Applied Sciences
This study investigates the impact of response time on ability estimation within an Item Response Theory (IRT) framework, introducing time-sensitive formulations to enhance student assessment accuracy.
Ahmet Hakan İnce, Serkan Özbay
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Adaptive soft sensor using stacking approximate kernel based BLS for batch processes

Scientific Reports
To deal with the highly nonlinear and time-varying characteristics of Batch Process, a model named adaptive stacking approximate kernel based broad learning system is proposed in this paper. This model innovatively introduces the approximate kernel based
Jinlong Zhao, Mingyi Yang, Zhigang Xu, Junyi Wang, Xiao Yang, Xinguang Wu   +5 more
doaj   +1 more source