Results 151 to 160 of about 1,241,988 (301)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Exploring adaptive capacity to arid heat in remote First Nations communities in Central Australia. [PDF]

Sci Rep
Bhatta M, Baliva G, Pascoe S, Talukder MR, Baghbanian V, Russell D, Ford L, Cass A, Wakerman J, Mathew S.   +9 more
europepmc   +1 more source

Contributions of phenotypic integration, plasticity and genetic adaptation to adaptive capacity relating to drought in Banksia marginata (Proteaceae). [PDF]

Front Plant Sci, 2023
Oyanoghafo OO, Miller AD, Toomey M, Ahrens CW, Tissue DT, Rymer PD.   +5 more
europepmc   +1 more source

Exploring the adaptive capacity of emergency management using agent based modelling [PDF]

This project aimed to explore the suitability of Agent Based Modelling and Simulation (ABMS) technology in assisting planners and policy makers to better understand complex situations with multiple interacting aspects. The technology supports exploration
Dhirendra Singh, Lin Padgham, Shae Hunter   +2 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The world's largest cities under climate change and their adaptive capacity to rising heat. [PDF]

Sci Rep
Friesen J, Taubenböck H.
europepmc   +1 more source

Exploring the role of leaders in enabling adaptive capacity in hospital teams - a multiple case study. [PDF]

BMC Health Serv Res, 2022
Fagerdal B, Lyng HB, Guise V, Anderson JE, Thornam PL, Wiig S.   +5 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Adaptive capacity of Asian populations of Lymantria dispar to non preferred plants during northward expansion. [PDF]

Sci Rep
Arzhanova EL, Pavlushin SV, Belousova IA, Akhanaev YB, Bastrygina AS, Martemyanov VV.   +5 more
europepmc   +1 more source