Results 161 to 170 of about 1,241,988 (301)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Short-term blood pressure variability as an indicator of the adaptive capacity of patients with chronic heart failure. [PDF]

open access: yesWorld J Exp Med
Akimova NS   +6 more
europepmc   +1 more source

A proactive learning approach toward building adaptive capacity during COVID-19: A radiology case study. [PDF]

open access: yesAppl Ergon, 2023
Hegde S   +6 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Assessing the adaptive capacity of smallholder cocoa farmers to climate variability in the Adansi South District of the Ashanti Region, Ghana. [PDF]

open access: yesHeliyon, 2023
Baffour-Ata F   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Dynamic capacity of adaptation

open access: yes, 2018
Fil: Garzón Castrillón, Manuel Alfonso. Fundación para la Investigación y el Desarrollo Educativo Empresarial. Grupo de Investigación; Colombia.
openaire   +1 more source

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