Results 121 to 130 of about 2,982,181 (249)

Dynamic Channel Allocation Techniques Using Adaptive Modulation and Adaptive Antennas

, 2001
This contribution studies the impact of adaptive quadrature amplitude modulation (AQAM) on network performance when applied to a cellular network, using adaptive antennas in conjunction with both fixed channel allocation (FCA) and locally distributed ...
Blogh, J.S., Cherriman, P.J., Hanzo, L.
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Asset pricing with adaptive learning [PDF]

We study the extent to which self-referential adaptive learning can explain stylized asset pricing facts in a general equilibrium framework. In particular, we analyze the effects of recursive least squares and constant gain algorithms in a production ...
Eva Carceles Poveda, Chryssi Giannitsarou   +1 more
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

From regime shifts to adaptive cycles: dynamic understanding of human-water system

Environmental Research: Water
Human-water systems are constantly changing over time. Regime shifts encompass large, abrupt and persistent structural and functional changes, leading the system to new reinforced processes or feedbacks. While existing research focuses on detecting early
Shuang Song, Lian Zhang, Jürgen Renn, Patrick Roberts   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Aircraft jet engines with adaptive cycle

, 2013
In this final bachelor thesis is a basic overview and distribution of gas turbine engines, including a brief description of their function. The work is focused on jet engines with adaptive cycle. It introduces benefits of their use as aviation fuel units
Heczko, Nikodem
core  

The MAORY first-light adaptive optics module for E-ELT

, 2015
The MAORY adaptive optics module is part of the first light instrumentation suite for the E-ELT. The MAORY project phase B is going to start soon.
Ragazzoni R., De Caprio V., Agapito G., Cortecchia F., Delboulbe A., Henault F., Riva M., Giro E., Bonaglia M., Lauria M., Pareschi G., Biliotti V., Briguglio R., Verinaud C., Esposito S., Busoni L., Spano P., Giordano C., Rochat S., Ramsay S., Bregoli G., Oberti S., Ferruzzi D., Ventura N., Arcidiacono C., Lafrasse S., Baruffolo A., Cascone E., Rabou P., Carbonaro L., Felini C., Schreiber L., Bellazzini M., Foppiani I., Xompero M., Roussel F., De Rosa A., Fiorentino G., De Pascale M., Ciliegi P., Ghigo M., Sztefek M. -H., Saracco P., Spavone M., Fini L., Magnard Y., Maurel D., Puglisi A., Roux A., Maiorano E., Le Coarer E., Di Rico G., Riccardi A., Morgante G., Cosentino G., Mapelli M., Moulin T., Fantinel D., Butler R. C., Jocou L., Lombini M., Marchetti E., Gluck L., Michaud L., Feautrier P., Zerbi F. M., Carlotti A., Diolaiti E., Ricciardi S., Abicca R., Mannucci F., Salasnich B., Zins G., Correia J. -J., Patti M., Stadler E., Casali M., Kerber F., Brissaud O., Del Vecchio C.   +79 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source