Results 51 to 60 of about 2,982,181 (249)
Dark adaptation and the retinoid cycle of vision
Progress in Retinal and Eye Research, 2004 Following exposure of our eye to very intense illumination, we experience a greatly elevated visual threshold, that takes tens of minutes to return completely to normal. The slowness of this phenomenon of "dark adaptation" has been studied for many decades, yet is still not fully understood.
Lamb, Trevor, Pugh, Edward N
openaire +3 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Duty Cycle Measurement Techniques for Adaptive and Resilient Autonomic Systems
, 2011 When systems are deployed in environments where change is the rule rather than the exception, adaptability and resilience play a crucial role in order to preserve good quality of service.
Riccardo Rovatti +5 more
core +1 more source
Navigating the adaptive cycle: an approach to managing the resilience of social systems
Ecology and Society, 2015 The concept of resilience continues to crescendo since the 1990s, touching on multiple fields with multiple interpretations and uses. Here, we start from its origins in systems ecology, framing the resilience concept explicitly in the adaptive cycle with
Brian D. Fath +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2020 This module covers the adaptive cycle, which is a conceptual model designed to help humans understand and manage how and why change occurs within common complex systems, such as ecosystems, societies, or economies.
Ludwig, Alison K. +6 more
core
Non-equilibrium thermodynamics and development cycles of temperate natural forest ecosystems
Folia Oecologica, 2018 The presented contribution in its first part summarizes several important theoretical findings of the system ecology supporting non-equilibrium paradigm of complex adaptive systems.
Urban Peter, Sabo Peter, Plesník Jan
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source