Results 61 to 70 of about 331,693 (264)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
THE CONCEPT OF RESILIENCE FROM A SUSTAINABLE DEVELOPMENT PERSPECTIVE [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2018 The resilience concept raises several conceptual problems, due to its multiple features. Once clarified the meaning of resilience concerning the science context, its paradigm reveals interdisciplinary nuances, which allow analysis of multiple phenomena
ANDREEA CONSTANTINESCU, SIMONA FRONE
doaj
Collapse and Recovery in Sahelian Agro-pastoral Systems: Rethinking Trajectories of Change
Ecology and Society, 2012 We discuss the adaptive cycle heuristic as a potential platform for describing the functioning and directions of change in Sahelian land use systems. Specifically, the aim is to go beyond the simplified narrative of a vicious circle of land degradation ...
Laura Vang Rasmussen, Anette Reenberg
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Ecology and Society, 2020 We used the adaptive cycle as a heuristic to conceptualize the changes in ecosystem services between its phases (growth, conservation, collapse, and reorganization) for Chiloé Island (southern Chile), analyzed as a social-ecological system.
Daniela C. Pérez-Orellana +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Ecology and Society, 2009 Large-scale government efforts to develop resources for societal benefit have often experienced cycles of growth and decline that leave behind difficult social and ecological legacies.
Colin M. Beier +2 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Retail resilience: A theoretical framework for understanding town centre dynamics
Studia Regionalne i Lokalne, 2015 The concept of resilience has gained much attention in recent academic and political discussion. However, its application to specific sectors, such as retail, is rather scarce.
Les Dolega, Dorota Celińska-Janowicz
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FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source