Results 71 to 80 of about 2,982,181 (249)
The commodification of peasant livelihoods through export-oriented aquaculture has brought about significant social-ecological changes in low-lying coastal areas in many parts of Asia.
Sonia F. Hoque +2 more
doaj +1 more source
Adaptive Planning Over the Cattle Price Cycle [PDF]
Cycles in beef cattle inventories and prices have been documented as far back as 1880 (Breimyer). The inability to identify optimal herd management strategies in response to fluctuating cattle prices is frequently blamed for the low historical returns received by cattle producers (Farris and Mallett).
Bentley, Ernest, Shumway, C. Richard
openaire +2 more sources
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Community-based conservation institutions can be conceptualized as complex adaptive systems that pass through a cycle of growth, maturation, collapse, and reorganization.
Nabin Baral +2 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Conceptualising Cluster Evolution: Beyond the Life-Cycle Model? [PDF]
Although the literature on the evolution of industrial clusters is not vast, a preferred approach has already become evident, based around the idea of a cluster 'life-cycle'. This approach has several limitations.
Peter Sunley, Ron Martin
core
Formalizing the Panarchy Adaptive Cycle with the Cusp Catastrophe [PDF]
The panarchy adaptive cycle, a general model for change in natural and human systems, can be formalized by the cusp catastrophe of René Thom\u27s topological theory.
Joshua Hughes +3 more
core +1 more source
Sustainable Development Integrated in the Concept of Resilence
The purpose of sustainable development is to minimize the likelihood of dynamic natural and/or man-made systems to exceed tipping points, when exposed to disturbances. In effect, the systems are protected from losing identity and integrity.
Jürg Bloesch +8 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

