Results 81 to 90 of about 2,982,181 (249)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Nuclear Fuel Cycle Royal Commission: Tentative findings
The Tentative Findings of the Nuclear Fuel Cycle Royal Commission are an interim step in the Commission’s process before the completion of the report in May 2016.
Nuclear Fuel Cycle Royal Commission
core
An adaptive aeroelastic control approach using non linear reduced order models [PDF]
A systematic approach to the model order reduction of high fidelity coupled fluid/structure/flight dynamics models and the subsequent control design is described. It uses information on the eigenspectrum of the coupled-system Jacobian matrix and projects
Palacios, R. +13 more
core +1 more source
Formalizing the Panarchy Adaptive Cycle with the Cusp Catastrophe [Presentation] [PDF]
The panarchy adaptive cycle, a general model for change in natural and human systems, can be formalized by the cusp catastrophe of René Thom\u27s topological theory.
Hughes, Joshua, Zwick, Martin
core +2 more sources
Rural transformation is important to deal with environmental change. In the context of rural transformation, institutional and policy changes have a great impact on farmers’ livelihoods. The adaptive cycle and the outcomes of farmers’ livelihoods reflect
Sha Yin, Xinjun Yang, Jia Chen
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Adaptive Timeslot Scheduling of Long Cycle Data in WIA-PA network
We consider the problem of finding an optimal and adaptive timeslot scheduling algorithm for long cycle data in WIA-PA network (ATS-LCD), which focuses on hybrid mesh and star network topology and a feedback mechanism that can significantly reduce ...
Yu HB(于海斌) +2 more
core
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
We tested the explanatory usefulness and policy relevance of Holling's (2001) "adaptive cycle" theory in exploring processes of "collapse," also called "release," and recovery in regional social-ecological systems (SESs) in Zimbabwe and Australia.
Nick Abel +2 more
doaj +1 more source

