Results 91 to 100 of about 2,040,374 (260)

Enhanced Lithium-Ion Battery State-of-Charge Estimation via Akima–Savitzky–Golay OCV-SOC Mapping Reconstruction and Bayesian-Optimized Adaptive Extended Kalman Filter

open access: yesEnergies
This paper introduces a novel Lithium-Ion Battery (LIB) State-of-Charge (SOC) estimation approach that integrates Akima–Savitzky–Golay curve reconstruction with a Bayesian-optimized, adaptive Extended Kalman Filter (EKF). The method addresses crucial SOC
Awang Abdul Hadi Isa   +3 more
doaj   +1 more source

Transcriptomic and macroevolutionary evidence for phenotypic uncoupling between frog life history phases

open access: yesNature Communications, 2017
In animals with complex life cycles, selection on one life phase may constrain adaptation in another phase. Here the authors find that, during the adaptive radiation of mantellid frogs, the evolution of tadpole and adult morphologies has been uncoupled ...
Katharina C. Wollenberg Valero   +12 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Business Cycles in India [PDF]

open access: yes
This paper describes business and growth rate cycles with special reference to the Indian economy. It uses the classical NBER approach to determine the timing of recessions and expansions in the Indian economy, as well as the chronology of growth rate ...
Pami Dua, Anirvan Banerji
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

EvoGraphCoder: An Evolutionary Graph-Reasoning Framework for Self-Adaptive Software Engineering

open access: yesIEEE Access
Modern software evolves rapidly, accumulates architectural debt, and develops cross-module dependencies that complicate reliable maintenance. We present EvoGraphCoder, an evolutionary graph-reasoning framework for self-adaptive software engineering ...
Karthik Ramamurthy   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Temperature adaptive self-regenerating ionic thermoelectric cycles for time domain thermal energy harvesting

open access: yesNature Communications
The rising demand for sustainable energy solutions has promoted significant interest in ionic thermoelectric materials, which convert low-grade waste heat into electrical energy through spatial temperature gradients.
Qikai Li   +8 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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