Results 91 to 100 of about 565,752 (296)
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
BatteriesThis paper develops a model for lithium-ion batteries under dynamic stress testing (DST) and federal urban driving schedule (FUDS) conditions that incorporates associated hysteresis characteristics of 18650-format lithium iron-phosphate batteries ...
Yujia Chang +3 more
doaj +1 more source
Iterative Implicit Methods for Solving Hodgkin-Huxley Type Systems
, 2019 We are motivated to approximate solutions of a Hodgkin-Huxley type model with implicit methods. As a representative we chose a psychiatric disease model containing stable as well as chaotic cycling behaviour.
Geiser, Juergen, Ogiermann, Dennis
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
From regime shifts to adaptive cycles: dynamic understanding of human-water system
Environmental Research: WaterHuman-water systems are constantly changing over time. Regime shifts encompass large, abrupt and persistent structural and functional changes, leading the system to new reinforced processes or feedbacks. While existing research focuses on detecting early
Shuang Song +3 more
doaj +1 more source
Driving-Cycle-Adaptive Energy Management Strategy for Hybrid Energy Storage Electric Vehicles
World Electric Vehicle JournalThe energy management strategy (EMS) is a critical technology for pure electric vehicles equipped with hybrid energy storage systems. This study addresses the challenges of limited adaptability to driving cycles and significant battery capacity ...
Zhaocheng Lu +3 more
doaj +1 more source
An endogenous crepuscular rhythm of rainbow trout (Salmo gairdneri) photomechanical movements [PDF]
, 1982 1. The position of the epithelial pigment and cones in the retina of Salmo gairdneri was determined during extended periods of darkness in fish entrained to both artificial and natural light/dark cycles. 2. An endogenous rhythm of such photomechanical
Douglas, R. H.
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A Coordinated Adaptive Signal Control Method Based on Queue Evolution and Delay Modeling Approach
Applied SciencesCoordinated adaptive signal control is a proven strategy for improving traffic efficiency and minimizing vehicular delays. First, we develop a Queue Evolution and Delay Model (QEDM) that establishes the relationship between detector-measured queue ...
Ruochen Hao +4 more
doaj +1 more source
On learning and the stability of cycles [PDF]
We study a general equilibrium model where the multiplicity of stationary periodic perfect foresight equilibria is pervasive. We investigate the extent of which agents can learn to coordinate on stationary perfect foresight cycles.
James Bullard, John Duffy
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