Results 111 to 120 of about 565,752 (296)

Enhanced Lithium-Ion Battery State-of-Charge Estimation via Akima–Savitzky–Golay OCV-SOC Mapping Reconstruction and Bayesian-Optimized Adaptive Extended Kalman Filter

Energies
This paper introduces a novel Lithium-Ion Battery (LIB) State-of-Charge (SOC) estimation approach that integrates Akima–Savitzky–Golay curve reconstruction with a Bayesian-optimized, adaptive Extended Kalman Filter (EKF). The method addresses crucial SOC
Awang Abdul Hadi Isa, Sheik Mohammed Sulthan, Muhammad Norfauzi Dani, Soon Jiann Tan   +3 more
doaj   +1 more source

Transcriptomic and macroevolutionary evidence for phenotypic uncoupling between frog life history phases

Nature Communications, 2017
In animals with complex life cycles, selection on one life phase may constrain adaptation in another phase. Here the authors find that, during the adaptive radiation of mantellid frogs, the evolution of tadpole and adult morphologies has been uncoupled ...
Katharina C. Wollenberg Valero, Joan Garcia-Porta, Ariel Rodríguez, Mónica Arias, Abhijeet Shah, Roger Daniel Randrianiaina, Jason L. Brown, Frank Glaw, Felix Amat, Sven Künzel, Dirk Metzler, Raphael D. Isokpehi, Miguel Vences   +12 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

EvoGraphCoder: An Evolutionary Graph-Reasoning Framework for Self-Adaptive Software Engineering

IEEE Access
Modern software evolves rapidly, accumulates architectural debt, and develops cross-module dependencies that complicate reliable maintenance. We present EvoGraphCoder, an evolutionary graph-reasoning framework for self-adaptive software engineering ...
Karthik Ramamurthy, Rahul Kumar Konduru, Nurmyrat Amanmadov   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Temperature adaptive self-regenerating ionic thermoelectric cycles for time domain thermal energy harvesting

Nature Communications
The rising demand for sustainable energy solutions has promoted significant interest in ionic thermoelectric materials, which convert low-grade waste heat into electrical energy through spatial temperature gradients.
Qikai Li, Mao Yu, Chunlin Pang, Xinya Wu, Shuaihua Wang, Huan Li, Yupeng Wang, Weishu Liu, Shien-Ping Feng   +8 more
doaj   +1 more source

Developing a panarchy model of landscape conservation and management of alpine-mountain grassland in Northern Italy. [PDF]

This paper explores methods of applying resilience theory to a case study of natural resource management and the cultural landscape of upland and alpine pasture in northern Italy.
Alessandro Gretter, Beatrice Marelli, Cristina Orsatti, Ian David Soane, Klaus Hubacek, Rocco Scolozzi   +5 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Stability and Cycles in a Cobweb Model with Heterogeneous Expectations [PDF]

We investigate the dynamics of a cobweb model with heterogeneous beliefs, generalizing the example of Brock and Hommes (1997). We examine situations where the agents form expectations by using either rational expectations, or a type of adaptive ...
Clem Tisdell, Laurence Lasselle, Serge Svizzero   +2 more
core