Results 111 to 120 of about 33,794 (307)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Adaptive fault identification for a class of nonlinear dynamic systems

, 2014
This paper is concerned with the diagnosis problem of actuator faults for a class of nonlinear systems. It is assumed that the upper bound of the Lipschtiz constant of the nonlinearity in the faulty system is unknown.
Ye D(叶丹), Zhao XG(赵新刚), Wu LB(武力兵)   +2 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Modelling and analyzing adaptive self-assembling strategies with Maude

Building adaptive systems with predictable emergent behavior is a challenging task and it is becoming a critical need. The research community has accepted the challenge by introducing approaches of various nature: from software architectures, to ...
Gadducci, Fabio, Lluch-Lafuente, Alberto, Bruni, Roberto, Corradini, Andrea, Vandin, Andrea   +4 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Using Numerical Dynamic Programming to Compare Passive and Active Learning in the Adaptive Management of Nutrients in Shallow Lakes

This paper illustrates the use of dual/adaptive control methods to compare passive and active adaptive management decisions in the context of an ecosystem with a threshold effect.
Loomis, John B., Bond, Craig A.
core  

An Adaptive Projection Differential Dynamic Programming Method for Control Constrained Trajectory Optimization

Mathematics
To address the issue of missing constraints on control variables in the trajectory optimization problem of the differential dynamic programming (DDP) method, the adaptive projection differential dynamic programming (AP-DDP) method is proposed.
Zhehao Xia, Yizhong Wu
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Optimal Regulation of Uncertain Dynamic Systems using Adaptive Dynamic Programming

, 2014
In this tutorial paper, the finite-horizon optimal adaptive regulation of linear and nonlinear dynamic systems with unknown system dynamics is presented in a forward-in-time manner using adaptive dynamic programming (ADP).
Xu, Hao, Zhao, Qiming, Jagannathan, S.
core   +1 more source

Integrating AI-based adaptive learning into the flipped classroom model to enhance engagement and learning outcomes

Computers and Education: Artificial Intelligence
This study explores the integration of the AI-powered adaptive learning system within the flipped classroom model and discusses programming education.
Jozsef Katona, Klara Ida Katonane Gyonyoru   +1 more
doaj   +1 more source