Results 181 to 190 of about 1,011,945 (297)

Accelerated mutator phenotype in a clinical <i>Aspergillus fumigatus</i> isolate contributes to adaptive evolution. [PDF]

Emerg Microbes Infect
Song Y, Hokken MWJ, Zoll J, Venselaar H, Verweij PE, Melchers WJG, Rhodes J.   +6 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Adaptive evolution of Agaricomycetes laccases follows wood lignin diversification in plants. [PDF]

Appl Environ Microbiol
Liu S, Yu Q, Yin T, Zhang X, Zhou R, Wang C, Xiao Y, Liu J, Fang Z.   +8 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

EVOLUTION AND ADAPTATION [PDF]

The American Journal of the Medical Sciences, 1904
openaire   +2 more sources

Genomic Instability and Adaptive Evolution Induced by RFA Insufficiency in <i>Saccharomyces cerevisiae</i>. [PDF]

Curr Issues Mol Biol
Zhang R, Tian L, He M, Li K.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Genetic diversity in Cyatheaceae in a stressful changing climate: a multi-omics review of adaptive evolution and conservation. [PDF]

Front Genet
Li T, Cong H, Rao D, Wu E, Cui Y, Gan R, Khan MN, Chen Y.   +7 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The Microtus fortis chromosome-level genome: illuminating adaptive evolution and natural parasite immunity. [PDF]

BMC Genomics
Zhang D, Zhou Q, Hu Q, He T, Xiao J, Zhou J, Wen Y, Liu Q, Zhang J, Zhi W, Ouyang L, Gao S, Guan R, Zhou Z.   +13 more
europepmc   +1 more source