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Journal of Allergy and Clinical Immunology, 2010
The innate immune system provides critical mechanisms for the rapid sensing and elimination of pathogens. Adaptive immunity has evolved to provide a broader and more finely tuned repertoire of recognition for both self- and nonself-antigens. Adaptive immunity involves a tightly regulated interplay between antigen-presenting cells and T and B ...
Francisco A, Bonilla, Hans C, Oettgen
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The innate immune system provides critical mechanisms for the rapid sensing and elimination of pathogens. Adaptive immunity has evolved to provide a broader and more finely tuned repertoire of recognition for both self- and nonself-antigens. Adaptive immunity involves a tightly regulated interplay between antigen-presenting cells and T and B ...
Francisco A, Bonilla, Hans C, Oettgen
+5 more sources
Adaptive immunity and atherosclerosis
Clinical Immunology, 2010Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most common causes of death globally. It has been evident for more than 20 years that adaptive immunity and T cells in particular regulate the magnitude of the atherogenic pro-inflammatory response.
Andersson J, Libby P, Hansson GK
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Critical Reviews™ in Immunology, 2011
Adaptive immunity, involving distinctive antibody- and cell-mediated responses to specific antigens based on "memory" of previous exposure, is a hallmark of higher vertebrates. It has been argued that adaptive immunity arose rapidly, as articulated in the "big bang theory" surrounding its origins, which stresses the importance of coincident whole ...
Clifford, Liongue +2 more
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Adaptive immunity, involving distinctive antibody- and cell-mediated responses to specific antigens based on "memory" of previous exposure, is a hallmark of higher vertebrates. It has been argued that adaptive immunity arose rapidly, as articulated in the "big bang theory" surrounding its origins, which stresses the importance of coincident whole ...
Clifford, Liongue +2 more
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Adaptive innate immunity or innate adaptive immunity?
Clinical Science, 2019AbstractThe innate immunity is frequently accepted as a first line of relatively primitive defense interfering with the pathogen invasion until the mechanisms of ‘privileged’ adaptive immunity with the production of antibodies and activation of cytotoxic lymphocytes ‘steal the show’.
Jan Černý, Ilja Stříž
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Neutrophils at the crossroads of innate and adaptive immunity
Journal of Leukocyte Biology, 2020Neutrophils are the most abundant leukocytes in blood. From the circulation, they are quickly mobilized to sites of inflammation and/or infection. At the affected tissues, neutrophils display an impressive array of antimicrobial functions, including ...
C. Rosales
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Adaptive immunity to mycobacteria
Current Opinion in Microbiology, 2004Advances are now being made in terms of understanding both the initiation of the adaptive or acquired response to tuberculosis infection and its interface with elements of the innate response, as well as much later events in terms of the chronic disease state where reactivation can potentially occur.
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Pyroptosis: The missing puzzle among innate and adaptive immunity crosstalk
Journal of Leukocyte Biology, 2020Pyroptosis is a newly discovered programmed cell death with inflammasome formation. Pattern recognition receptors that identify repetitive motifs of prospective pathogens such as LPS of gram‐negative bacteria are crucial to pyroptosis.
M. Hachim +3 more
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