Results 111 to 120 of about 1,158,420 (335)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Decision Support in Cognitive Information Systems: Carbon–Silicon Infocommunication

open access: yesIEEE Access
This paper examines the role of Cognitive Information Systems (CIS) in enterprise decision support, emphasizing Carbon-Silicon agent infocommunication.
Attila Marton Putnoki   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Cloud-based adaptive exon prediction for DNA analysis

open access: yesHealthcare Technology Letters, 2018
Cloud computing offers significant research and economic benefits to healthcare organisations. Cloud services provide a safe place for storing and managing large amounts of such sensitive data.
Srinivasareddy Putluri   +2 more
doaj   +1 more source

Measuring the degree of virtualization. An empirical analysis in two Austrian industries. [PDF]

open access: yes, 2002
Strategic management literature suggests that especially in young and dynamic industries Virtual Corporations are more likely to emerge, as this type of organization is flexible enough to deal with rapidly changing environments. This paper challenges the
Bauer, Roland   +2 more
core  

Logarithmic mathematical morphology: a new framework adaptive to illumination changes

open access: yes, 2018
A new set of mathematical morphology (MM) operators adaptive to illumination changes caused by variation of exposure time or light intensity is defined thanks to the Logarithmic Image Processing (LIP) model. This model based on the physics of acquisition
AV Oppenheim   +11 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Application of wireless sensor network based on improved genetic algorithm in English blended learning

open access: yesMeasurement: Sensors
Adaptive genetic algorithm is one of the classic algorithms to solve multi-objective optimization problems. In order to make the convergence set to the Pareto boundary more uniform, this article improves how to compare multiple distances in the algorithm,
Guo Yuanda
doaj   +1 more source

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