Results 121 to 130 of about 18,932,286 (290)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

ANGIE: Adaptive Network for Granular Information and Evidence Processing

In this paper the possibility of using adaptive networks in fuzzy-evidence-based decision support systems is considered. The architecture and learning algorithm underlying ANGIE (adaptive network for granular information processing) is presented.
Vališevskis, Aleksandrs, Borisovs, Arkādijs   +1 more
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Exploring the Impact of Adaptive Behaviors on Balance: A Comparative Analysis of Static and Dynamic Balance in Athletes With and Without Intellectual Disabilities

Brain and Behavior
Background Individuals with intellectual disability (ID) shows less development on their motor skills. Understanding the interaction between intellectual and physical performance will provide valuable information for the design of personalized ...
Elisa Benito‐Martínez, Beatriz Alonso‐Cortés, Mario Fernández‐Gorgojo, Raul Coto Martín, Ricardo Méndez Blanco   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Adaptive User Support in Interactive Information Retrieval Processes.

, 2017
In unserem beruflichen als auch privaten Umfeld verfolgen wir regelmäßig bestimmte Ziele, bei denen es darum geht, ein bestimmtes Ergebnis oder einen angedachten Soll-Zustand zu erreichen. Die berufliche Tätigkeit und die privaten Interessen geben dabei in der Regel vor, welche Ziele eine Person verfolgt.
openaire   +2 more sources

Adaptive simulated annealing for optimization in signal processing applications

, 1999
Many signal processing applications pose optimization problems with multimodal and nonsmooth cost functions. Gradient methods are ineffective in these situations. The adaptive simulated annealing (ASA) offers a viable optimization tool for tackling these
Luk, B. L., Chen, S.
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

An extensible open-source solution for research digitalisation in materials science

npj Computational Materials
Information technology and data science development stimulate transformation in many fields of scientific knowledge. In recent years, a large number of specialised systems for information and knowledge management have been created in materials science ...
Victor Dudarev, Lars Banko, Alfred Ludwig   +2 more
doaj   +1 more source