Results 121 to 130 of about 1,158,420 (335)

Information-constrained optimization: can adaptive processing of gradients help? [PDF]

open access: green, 2021
Jayadev Acharya   +3 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Activity flow under the manipulation of cognitive load and training

open access: yesNeuroImage
Flexible cognitive functions, such as working memory (WM), usually require a balance between localized and distributed information processing. However, it is challenging to uncover how local and distributed processing specifically contributes to task ...
Wanyun Zhao   +7 more
doaj   +1 more source

Adaptive User Support in Interactive Information Retrieval Processes. [PDF]

open access: yes, 2017
In our everyday lives, we pursue different goals that apply in both our professional and private context. These goals can be short-term or long-term, and can be extensive, difficult or complex. Goals can be specified or instructed by others (e.g., a supervisor), or by ourselves (e.g., a hobby).
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Few-shot action recognition in video method based on second-order spatiotemporal adaptation

open access: yes河南理工大学学报. 自然科学版
ObjectivesIn the field of few-shot video action recognition, existing methods generally face challenges in adequately processing global spatiotemporal information.
Zhang Bingbing   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Elements of learning technologies designing of engineering networks heat

open access: yesSHS Web of Conferences, 2016
Modern educational systems function as a medium fast analysis of shared information that defines them as analytical. The purpose of analytical information processing systems: working with distributed data on a global computer networks, mining and ...
Sidorkina Irina G., Sorokin Oleg L.
doaj   +1 more source

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