Results 141 to 150 of about 1,158,420 (335)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Brain and BehaviorBackground Individuals with intellectual disability (ID) shows less development on their motor skills. Understanding the interaction between intellectual and physical performance will provide valuable information for the design of personalized ...
Elisa Benito‐Martínez +4 more
doaj +1 more source
Automating security monitoring and analysis for Space Station Freedom's electric power system [PDF]
Operating a large, space power system requires classifying the system's status and analyzing its security. Conventional algorithms are used by terrestrial electric utilities to provide such information to their dispatchers, but their application aboard ...
Dolce, James L. +2 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Adaptive information processing of network modules to dynamic and spatial stimuli. [PDF]
BMC Syst Biol, 2019 Krishnan J, Floros I.
europepmc +1 more source
Adaptation and validation of a social information processing assessment procedure for research
Child NeuropsychologyBiases and deficits in social information processing (SIP) skills are associated with social maladjustment in children and adolescents. There is much literature on the association between processing skills and their relationship to aggressive behavior, but there is limited knowledge about their association with other types of antisocial behavior.
Beatriz Ortega Vidal +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
An extensible open-source solution for research digitalisation in materials science
npj Computational MaterialsInformation technology and data science development stimulate transformation in many fields of scientific knowledge. In recent years, a large number of specialised systems for information and knowledge management have been created in materials science ...
Victor Dudarev +2 more
doaj +1 more source