Results 121 to 130 of about 6,281,815 (256)

Annual Report - Marine Biological Laboratory, 1894

open access: yes, 1895
Annual report of the Marine Biological Laboratory in Woods Hole. 1894.
Marine Biological Laboratory (Woods Hole MA)
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Adaptive Reptile Color Variation and the Evolution of the MC1R Gene

open access: yes, 2014
The wealth of information on the genetics of pigmentation and the clear fitness consequences of many pigmentation phenotypes provide an opportunity to study the molecular basis of an ecologically important trait.
Rosenblum, Erica Bree   +2 more
core   +1 more source

Micro-droplet based directed evolution outperforms conventional laboratory evolution

open access: yes, 2015
We present droplet adaptive laboratory evolution (DrALE), a directed evolution method used to improve industrial enzyme producing microorganisms for e.g. feedstock digestion. DrALE is based linking a desired phenotype to growth rate allowing only desired
Svahn, H. A.   +8 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1888

open access: yes, 1889
Annual report of the Marine Biological Laboratory in Woods Hole. 1888.
Marine Biological Laboratory (Woods Hole MA)
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1892

open access: yes, 1892
Annual report of the Marine Biological Laboratory in Woods Hole. 1892.
Marine Biological Laboratory (Woods Hole MA)
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1896-1902

open access: yes, 1902
Annual report of the Marine Biological Laboratory in Woods Hole for the years 1896-1899.
Marine Biological Laboratory (Woods Hole MA)
core  

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