Results 41 to 50 of about 10,453,390 (281)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Terrain-Adaptive Global Path Planning Method Based on Bidirectional Variable Neighborhood Search A*

Actuators
To address the issues of low efficiency and non-smooth paths of the A* algorithm in large-scale environments, a terrain-adaptive global path planning method based on Bidirectional Variable Neighborhood Search A* (Terrain-Adaptive Bidirectional Variable ...
Ze Zhang, Ke Liu, Yulong Lei, Yao Fu, Yutong Liu   +4 more
doaj   +1 more source

An Adaptive Sand Cat Swarm Algorithm Based on Cauchy Mutation and Optimal Neighborhood Disturbance Strategy

Biomimetics, 2023
Sand cat swarm optimization algorithm (SCSO) keeps a potent and straightforward meta-heuristic algorithm derived from the distant sense of hearing of sand cats, which shows excellent performance in some large-scale optimization problems.
Xing Wang, Qian Liu, Li Zhang
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

Emergency Relief Material Distribution Path Optimization Under Multiple Constraints

Applied Sciences
To overcome the limitations of traditional methods in emergency response scenarios—such as limited adaptability during the search process and a tendency to fall into local optima, which reduce the overall efficiency of emergency supply distribution—this ...
Haoran He, Xiaoxiong Zhang, Qiang Fan, Jun Yang, Xiaolei Zhou, Bing Yu   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Robust Optimization for Electric Vehicle Routing Problem Considering Time Windows Under Energy Consumption Uncertainty

Applied Sciences
Compared to fossil fuel-based internal combustion vehicles, electric vehicles with lower local pollution and noise are becoming more and more popular in urban logistic distribution.
Dan Wang, Weibo Zheng, Hong Zhou
doaj   +1 more source

Adaptive particle swarm optimization [PDF]

, 2009
An adaptive particle swarm optimization (APSO) that features better search efficiency than classical particle swarm optimization (PSO) is presented. More importantly, it can perform a global search over the entire search space with faster convergence ...
Zhan, Z-H., Li, Y., Chung, H.S-H., Zhang, J.   +3 more
core   +1 more source

Very Large-Scale Neighborhood Search

, 2021
Very Large-Scale Neighborhood Search is not an algorithm or a class of algorithms, but rather a conceptual framework which can be used for solving combinatorial optimization problems. The approach “concentrates on neighborhood search algorithms where the
Thomas Stützle, Boschetti, Marco Antonio, Stützle, Thomas, Marco Antonio Boschetti, Maniezzo, Vittorio, Vittorio Maniezzo   +5 more
core   +1 more source