Results 61 to 70 of about 10,453,390 (281)

A Neighborhood Search for Sequence-dependent Setup Time in Flow Shop Fabrics Making of Textile Industry [PDF]

, 2011
This paper proposes a neighborhood search to solve scheduling for fabrics making in a textile industry. The production process consists of three production stages from spinning, weaving, and dyeing. All stages have one processor.
Totong,, Kurniawan, Bobby, Sumihartati, Atin   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Research on Route Optimization of Single-Supply-Point Perishable Goods Multimodal Transport Considering Transportation Vibration Loss

Mathematics
As the market of perishable goods in China continues to expand, reducing quality loss during transportation has become an urgent issue for the industry.
Yang Xu, Mei-Juan Ma, Xin Zhang, Bin Su, Meng Zhang, Qing-E Guo   +5 more
doaj   +1 more source

Adaptive Large Neighborhood Search for Multitrip Vehicle Routing with Time Windows [PDF]

Transportation Science, 2019
We consider a multitrip vehicle routing problem with time windows (MTVRPTW), in which each vehicle can perform several trips during its working shift. This problem is especially relevant in the context of city logistics. Heuristic solution methods for multitrip vehicle routing problems often separate routing and assignment phases to create trips and ...
Véronique François, Yasemin Arda, Yves Crama   +2 more
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Adaptive Anytime Multi-Agent Path Finding Using Bandit-Based Large Neighborhood Search [PDF]

Anytime multi-agent path finding (MAPF) is a promising approach to scalable path optimization in large-scale multi-agent systems. State-of-the-art anytime MAPF is based on Large Neighborhood Search (LNS), where a fast initial solution is iteratively ...
Phan, Thomy, Huang, Taoan, Koenig, Sven, Dilkina, Bistra   +3 more
core   +3 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Reinforced Adaptive Large Neighborhood Search

, 2011
The Large Neighborhood Search metaheuristic for solving Constrained Optimization Problems has been proved to be effective on a wide range of problems.
Deville, Yves, Van Hentenryck, Pascal, Eightth International Workshop on Local Search Techniques in Constraint Satisfaction (LSCS2011), Mairy, Jean-Baptiste   +3 more
core