Results 51 to 60 of about 12,176,108 (293)

Path optimization of trackless rubber-tyred vehicles in bidirectional single-lane underground coal mine roadways

Gong-kuang zidonghua
Bidirectional single-lane roadways are widely present in underground auxiliary transportation roadways of coal mines, where vehicles traveling in opposite directions must rely on passing bays for meeting and yielding, and multi-vehicle parallel ...
MAO Songsong, ZHENG Mingtao, LI Chao, XI Kang, YANG Junqi   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Parallel adaptive large neighborhood search based on spark to solve VRPTW

Scientific Reports
Aiming at the multi-objective vehicle path planning problem with time windows (VRPTW), a Spark-based parallel Adaptive Large Neighborhood Search algorithm (Spark-ALNS) is proposed to solve it.
Songzuo Liu, Jian Sun, Xiaohong Duan, Guofang Liu   +3 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

eVTOL Route Planning for Urban Low-Altitude Bus Services Considering Dynamic Passenger Load Variations and Battery Safety Constraints

Mathematics
Urban low-altitude bus operations require coordinated eVTOL route decisions under station time windows, dynamic passenger boarding and alighting, load-dependent energy consumption, opportunity charging, and battery safety requirements.
Guohua Wu, Wen Xie, Guangzhi Wang, Fangyu Hong, Fen Xing   +4 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Improved Differential Evolution Algorithm to Solve the Advertising Method Selection Problem

Journal of Open Innovation: Technology, Market and Complexity, 2019
This article proposes a methodology to resolve the advertising method selection problem (AdSP). The use of different advertising methods for the same product can generate different responses in terms of the product’s sales volume. Companies selling
Malichan Thongkham, Tassin Srivarapongse
doaj   +1 more source

Joint Distribution Location-routing Problem and Large Neighborhood Search Algorithm

, 2021
: Based on the characteristics of two-echelon, multi-center, and heterogeneous fleets in urban logistics joint distribution system, the two-echelon joint distribution location routing problem is studied.
Xing, Lining, Zhang, Yuwei, Zhao, Yuwei, Teng, Ren, Li, Zhenping   +4 more
core   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source