Results 71 to 80 of about 188,879 (245)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
EnergiesThe voltage source converter-based multi-terminal DC transmission (VSC-MTDC) system can use additional frequency control to respond to the frequency change of faulty AC system.
Chao Xing +7 more
doaj +1 more source
Attention modulates generalization of visuomotor adaptation
Journal of Vision, 2013 Generalization represents the ability to transfer what has been learned in one context to another context beyond limited experience. Because acquired motor representations often have to be reinstated in a different or novel environment, generalization is a crucial part of visuomotor learning. In daily life, training for new motor skills often occurs in
Patrick, Bédard, Joo-Hyun, Song
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Physical layer security of MIMO wireless systems with adaptive modulation
Dianxin kexue, 2023 To solve the problems of low spectral efficiency and poor performance of physical layer security (PLS) in single-input single-output (SISO) wireless systems with adaptive modulation in the presence of an active eavesdropper, multiple-input multiple ...
Hui LI +3 more
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Optimum mode-switching assisted adaptive modulation
GLOBECOM'01. IEEE Global Telecommunications Conference (Cat. No.01CH37270), 2002 Adaptive modulation techniques combat fading by employing a suitable modulation mode depending on the instantaneous channel conditions for improving the Bit Error Rate (BER) performance or the average throughput. Based on a generic model of constant-power adaptive modulation, exact closed form expressions of the average BER and the average throughput ...
Choi, B.J., Hanzo, L.
openaire +2 more sources
Intrinsic Gain Modulation and Adaptive Neural Coding
PLoS Computational Biology, 2008 24 pages, 4 figures, 1 supporting ...
Sungho Hong +2 more
openaire +5 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source