Results 91 to 100 of about 145,188 (319)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Ground-Based Coronagraphy with High Order Adaptive Optics [PDF]

, 2001
We summarize the theory of coronagraphic optics, and identify a dimensionless fine-tuning parameter, F, which we use to describe the Lyot stop size in the natural units of the coronagraphic optical train and the observing wavelength.
Anand Sivaramakrishnan, Christopher D. Koresko, Fried D. L., Glindemann A., Golimowski D. A., Lyot B., Malbet F., Marc J. Kuchner, Noll R. J., Russell B. Makidon, Thomas Berkefeld, Wang T.   +11 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

FALCON: a concept to extend adaptive optics corrections to cosmological fields [PDF]

, 2004
FALCON is an original concept for a next generation spectrograph at ESO VLT or at future ELTs. It is a spectrograph including multiple small integral field units (IFUs) which can be deployed within a large field of view such as that of VLT/GIRAFFE.
, , Arnaud Liotard, Eric Gendron, Francois F. Assemat, Francois Hammer, Frederic Sayede, Frederic Zamkotsian, Mathieu Puech, Michel Marteaud, Philippe Laporte   +10 more
core   +4 more sources

Control Bandwidth Promotion of Adaptive Fiber-Optics Collimator and Its Application in Coherent Beam Combination

IEEE Photonics Journal, 2018
Adaptive fiber-optics collimator (AFOC) plays an important role in the coherent beam combining (CBC) systems. To improve the control bandwidth, the frequency characteristics of AFOC are measured, and an accurate transfer function model is established ...
Guan Huang, Chao Geng, Feng Li, Jiaying Liu, Xinyang Li   +4 more
doaj   +1 more source

Modular adaptive optics solution for a QKD receiver on a fork mount telescope system [PDF]

, 2021
Edgar Fischer, K. Kudielka, Aoife Brady, Andreas Kamm, Thomas Berkefeld, Rupert Ursin   +5 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Adaptive Optics: introduction to the feature issue [PDF]

, 2010
This Applied Optics feature issue is a companion to the Journal of the Optical Society of America A feature issue on the same topic. The feature highlights the expansion of adaptive optics to different applications as well as its development to routine ...
Christou, Julian, Ellerbroek, Brent L., Fusco, Thierry, Miller, Donald T.   +3 more
core  

Correlated Photon Lidar Based on Time-Division Multiplexing

Photonics
Single-photon lidar (SPL) exhibits high sensitivity, making it particularly suitable for detecting weak echoes over long distances. However, its susceptibility to background noise necessitates the implementation of advanced filtering techniques and ...
Yun Jiang, Bo Liu, Zixun Wang, Fengyun Huang, Taibei Liu, Lan Luo, Feifan He, Yongqi Yang, Bin Zhao   +8 more
doaj   +1 more source