Results 101 to 110 of about 2,920,675 (338)

Adaptive Optics Photoreceptor Imaging

open access: yesOphthalmology, 2012
In the present study, we investigated the cone packing density distribution along the horizontal meridian passing through the fovea in a population of young healthy subjects using a compact Adaptive Optics (AO) retinal camera (rtx1, Imagine Eyes, Orsay, France).
M Lombardo   +3 more
openaire   +7 more sources

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

Functional retinal imaging using adaptive optics swept-source OCT at 1.6MHz

open access: yesbioRxiv, 2018
Objective optical assessment of photoreceptor function may permit earlier diagnosis of retinal disease than current methods such as perimetry, electrophysiology, and clinical imaging.
Mehdi Azimipour   +4 more
semanticscholar   +1 more source

INTRACAVITY ADAPTIVE OPTICS

open access: yesLe Journal de Physique Colloques, 1980
A major consideration in most laser resonator designs for high power is to obtain the maximum far field irradiance on a target. Various design approaches have emerged in recent years to optimize the far-field irradiance by utilizing different resonator concepts for the purpose of obtaining the best mode control and near field beam quality.
J. M. Spinhirne, R. H. Freeman, D. Anafi
openaire   +2 more sources

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Trans-retinal cellular imaging with multimodal adaptive optics

open access: yesBiomedical Optics Express, 2018
Adaptive optics (AO), when coupled to different imaging modalities, has enabled resolution of various cell types across the entire retinal depth in the living human eye.
Zhuolin Liu   +3 more
semanticscholar   +1 more source

Correlated Photon Lidar Based on Time-Division Multiplexing

open access: yesPhotonics
Single-photon lidar (SPL) exhibits high sensitivity, making it particularly suitable for detecting weak echoes over long distances. However, its susceptibility to background noise necessitates the implementation of advanced filtering techniques and ...
Yun Jiang   +8 more
doaj   +1 more source

Beyond p‐values: Assessing clinical significance in acupuncture research

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley   +1 more source

Active PSF Shaping and Adaptive Optics Enable Volumetric Localization Microscopy through Brain Sections

open access: yesNature Methods, 2018
Application of single-molecule switching nanoscopy (SMSN) beyond the coverslip surface poses substantial challenges due to sample-induced aberrations that distort and blur single-molecule emission patterns.
Michael J. Mlodzianoski   +8 more
semanticscholar   +1 more source

Control Bandwidth Promotion of Adaptive Fiber-Optics Collimator and Its Application in Coherent Beam Combination

open access: yesIEEE Photonics Journal, 2018
Adaptive fiber-optics collimator (AFOC) plays an important role in the coherent beam combining (CBC) systems. To improve the control bandwidth, the frequency characteristics of AFOC are measured, and an accurate transfer function model is established ...
Guan Huang   +4 more
doaj   +1 more source

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