Results 51 to 60 of about 26,046 (295)

Adaptive optics – basic optical principles

Acta Ophthalmologica, 2016
SummaryAdaptive Optics (AO) refers to a technique to compensate for distortions caused by optical aberrations in the media between the camera and the object being imaged. It was originally developed for use in astronomical telescopes to compensate for optical distortions induced by the inhomogeneous earth atmosphere.
openaire   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Adaptive optics in laser processing [PDF]

Light: Science & Applications, 2019
AbstractAdaptive optics are becoming a valuable tool for laser processing, providing enhanced functionality and flexibility for a range of systems. Using a single adaptive element, it is possible to correct for aberrations introduced when focusing inside the workpiece, tailor the focal intensity distribution for the particular fabrication task and/or ...
Salter, P, Booth, M
openaire   +4 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

ESL-YOLO: Small Object Detection with Effective Feature Enhancement and Spatial-Context-Guided Fusion Network for Remote Sensing

Remote Sensing
Improving the detection of small objects in remote sensing is essential for its extensive use in various applications. The diminutive size of these objects, coupled with the complex backgrounds in remote sensing images, complicates the detection process.
Xiangyue Zheng, Yijuan Qiu, Gang Zhang, Tao Lei, Ping Jiang   +4 more
doaj   +1 more source

Real-Time Controller Based on FPGA and DSP for Solar Ground Layer Adaptive Optics Prototype System at 1-m NVST

IEEE Photonics Journal, 2017
Solar ground layer adaptive optics (GLAO), containing a large field of view (FOV) wavefront sensor (WFS) and one deformable mirror (DM), can be used to reduce and stabilize the seeing effectively over a wide FOV. As the brain of the GLAO system, the real-
Lin Kong, Lei Zhu, Lanqiang Zhang, Hua Bao, Changhui Rao   +4 more
doaj   +1 more source

Adaptive Optical Scanning Holography [PDF]

Scientific Reports, 2016
AbstractOptical Scanning Holography (OSH) is a powerful technique that employs a single-pixel sensor and a row-by-row scanning mechanism to capture the hologram of a wide-view, three-dimensional object. However, the time required to acquire a hologram with OSH is rather lengthy.
Ting-Chung Poon, Jung-Ping Liu, Peter Wai Ming Tsang   +2 more
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Infrared Small Target Detection via Multidirectional Local Gravitational Force and Level-Line Connectivity

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Infrared small target detection is significantly challenged by residual high-intensity background edges and a low signal-to-noise ratio. These issues hinder accurate target differentiation from the background and heighten the risk of false alarms.
Xuying Hao, Xianyuan Liu, Yujia Liu, Yijuan Qiu, Yunjing Zhang, Yi Cui, Tao Lei   +6 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source