Results 61 to 70 of about 145,669 (318)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Development of a scalable generic platform for adaptive optics real time control

open access: yes, 2015
The main objective of the present project is to explore the viability of an adaptive optics control system based exclusively on Field Programmable Gate Arrays (FPGAs), making strong use of their parallel processing capability.
Burse, Mahesh P.   +3 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

ESL-YOLO: Small Object Detection with Effective Feature Enhancement and Spatial-Context-Guided Fusion Network for Remote Sensing

open access: yesRemote Sensing
Improving the detection of small objects in remote sensing is essential for its extensive use in various applications. The diminutive size of these objects, coupled with the complex backgrounds in remote sensing images, complicates the detection process.
Xiangyue Zheng   +4 more
doaj   +1 more source

Real-Time Controller Based on FPGA and DSP for Solar Ground Layer Adaptive Optics Prototype System at 1-m NVST

open access: yesIEEE Photonics Journal, 2017
Solar ground layer adaptive optics (GLAO), containing a large field of view (FOV) wavefront sensor (WFS) and one deformable mirror (DM), can be used to reduce and stabilize the seeing effectively over a wide FOV. As the brain of the GLAO system, the real-
Lin Kong   +4 more
doaj   +1 more source

Integrated Laboratory Demonstrations of Multi-Object Adaptive Optics on a Simulated 10-Meter Telescope at Visible Wavelengths [PDF]

open access: yes, 2009
One important frontier for astronomical adaptive optics (AO) involves methods such as Multi-Object AO and Multi-Conjugate AO that have the potential to give a significantly larger field of view than conventional AO techniques.
Ammons, S. Mark   +6 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Infrared Small Target Detection via Multidirectional Local Gravitational Force and Level-Line Connectivity

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Infrared small target detection is significantly challenged by residual high-intensity background edges and a low signal-to-noise ratio. These issues hinder accurate target differentiation from the background and heighten the risk of false alarms.
Xuying Hao   +6 more
doaj   +1 more source

Study of a MEMS-based Shack-Hartmann wavefront sensor with adjustable pupil sampling for astronomical adaptive optics [PDF]

open access: yes, 2008
We introduce a Shack-Hartmann wavefront sensor for adaptive optics that enables dynamic control of the spatial sampling of an incoming wavefront using a segmented mirror microelectrical mechanical systems (MEMS) device.
Baranec, Christoph, Dekany, Richard
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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