Results 81 to 90 of about 145,669 (318)

On-sky wide field adaptive optics correction using multiple laser guide stars at the MMT [PDF]

, 2008
We describe results from the first astronomical adaptive optics system to use multiple laser guide stars, located at the 6.5-m MMT telescope in Arizona. Its initial operational mode, ground-layer adaptive optics (GLAO), provides uniform stellar wavefront
Baranec, Baranec, Baranec, Baranec, Boccas, Casali, Christoph Baranec, Craig Kulesa, Don McCarthy, Egner, Ellerbroek, Freed, Gavel, Georges, Gilmozzi, Hinz, Keith Powell, Lloyd-Hart, Lloyd-Hart, Lloyd-Hart, Lloyd-Hart, Marchetti, Martin, McCarthy, Michael Hart, Miguel Snyder, Milton, N. Mark Milton, Pickering, Putnam, Rigaut, Stalcup, Szeto, Thomas Stalcup, Tokovinin, Vaitheeswaran, Velur, Verin, Vidhya Vaitheeswaran, Wildi, Wizinowich   +40 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A Reparameterization Feature Redundancy Extract Network for Unmanned Aerial Vehicles Detection

Remote Sensing
In unmanned aerial vehicles (UAVs) detection, challenges such as occlusion, complex backgrounds, motion blur, and inference time often lead to false detections and missed detections.
Shijie Zhang, Xu Yang, Chao Geng, Xinyang Li   +3 more
doaj   +1 more source

Laboratory Testing the Layer Oriented Wavefront Sensor for the Multiconjugate Adaptive optics Demonstrator

, 2009
The Multiconjugate Adaptive optics Demonstrator (MAD) for ESO-Very Large Telescopes (VLT) will demonstrate on sky the MultiConjugate Adaptive Optics (MCAO) technique.
Arcidiacono, Carmelo, Diolaiti, Emiliano, Farinato, Jacopo, Lombini, Matteo, Ragazzoni, Roberto   +4 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Adaptive optics for optical microscopy [Invited]

Biomedical Optics Express, 2023
Optical microscopy is widely used to visualize fine structures. When applied to bioimaging, its performance is often degraded by sample-induced aberrations. In recent years, adaptive optics (AO), originally developed to correct for atmosphere-associated aberrations, has been applied to a wide range of microscopy modalities, enabling high- or super ...
Zhang, Q, Hu, Q, Berlage, C, Kner, P, Judkewitz, B, Booth, M, Ji, N   +6 more
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Quantitative assessment of parameter requirements in a division of focal plane polarimeter

Scientific Reports
The division of focal plane polarimeter (DoFP) is a widely utilized instrument for target detection and recognition, owing to its excellent real-time performance and compact configuration.
Bowen Lian, Jingpeng Yang, Ao Tang, Yawei Xiao, Naiting Gu   +4 more
doaj   +1 more source

Control Bandwidth Promotion of Adaptive Fiber-Optics Collimator and Its Application in Coherent Beam Combination

IEEE Photonics Journal, 2018
Adaptive fiber-optics collimator (AFOC) plays an important role in the coherent beam combining (CBC) systems. To improve the control bandwidth, the frequency characteristics of AFOC are measured, and an accurate transfer function model is established ...
Guan Huang, Chao Geng, Feng Li, Jiaying Liu, Xinyang Li   +4 more
doaj   +1 more source

The Robo-AO-2 facility for rapid visible/near-infrared AO imaging and the demonstration of hybrid techniques [PDF]

, 2018
We are building a next-generation laser adaptive optics system, Robo-AO-2, for the UH 2.2-m telescope that will deliver robotic, diffraction-limited observations at visible and near-infrared wavelengths in unprecedented numbers.
Baranec, Christoph, Chun, Mark, Connelley, Michael, de Pater, Imke, Dekany, Richard, Griffiths, Richard, Guyon, Olivier, Hall, Donald, Hammel, Heidi, Hodapp, Klaus, Huber, Daniel, Kasliwal, Mansi, Kissler-Patig, Markus, Kuchner, Marc, Lau, Ryan, Law, Nicholas M., Liu, Michael, Magnier, Eugene, Meech, Karen, Moore, Anna, Ofek, Eran, Riddle, Reed, Simon, Amy, Takamiya, Marianne, van Dam, Marcos A., Wong, Mike   +25 more
core   +1 more source