Results 51 to 60 of about 21,086 (310)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Micro-machined membrane deformable mirrors for cryogenic adaptive optics [PDF]

, 2002
In this Thesis, the suitability of 37 actuator Micro-machined membrane deformable mirrors (MMDM) for adaptive optics at cryogenic temperatures is evaluated. A method is described to safely cool MMDMs to 78K. The initial surface figures of three MMDMs are
Dyson, H.M., Dyson, Harold Michael
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Research on Adaptive Optics Image Restoration Algorithm by Improved Expectation Maximization Method

Abstract and Applied Analysis, 2014
To improve the effect of adaptive optics images’ restoration, we put forward a deconvolution algorithm improved by the EM algorithm which joints multiframe adaptive optics images based on expectation-maximization theory.
Lijuan Zhang, Dongming Li, Wei Su, Jinhua Yang, Yutong Jiang   +4 more
doaj   +1 more source

Interferometric wavefront sensing for extreme adaptive optics [PDF]

, 2004
Adaptive optics is concerned with the correction of phase distortions in wavefronts which degrade the quality of images produced by optical systems. It was originally developed for both astronomy and the military, where the Earth's atmosphere causes ...
Oag, Thomas J. D., Oag, Thomas J D
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Insights into Sickle Cell Disease through the Retinal Microvasculature

Ophthalmology Science, 2022
Purpose: Clinical OCT angiography (OCTA) of the retinal microvasculature offers a quantitative correlate to systemic disease burden and treatment efficacy in sickle cell disease (SCD).
Alexander Pinhas, MD, Justin V. Migacz, PhD, Davis B. Zhou, MD, Maria V. Castanos Toral, MD, Oscar Otero-Marquez, MD, Sharon Israel, BA, Vincent Sun, MD, Peter N. Gillette, MD, Nripun Sredar, PhD, Alfredo Dubra, PhD, Jeffrey Glassberg, MD, Richard B. Rosen, MD, Toco Y.P. Chui, PhD   +12 more
doaj   +1 more source

The numerical simulation tool for the MAORY multiconjugate adaptive optics system [PDF]

, 2016
The Multiconjugate Adaptive Optics RelaY (MAORY) is and Adaptive Optics module to be mounted on the ESO European-Extremely Large Telescope (E-ELT).
XOMPERO, MARCO, M. Xompero, FOPPIANI, ITALO, S. Oberti, Cosentino, Giuseppe, G. Cosentino, SCHREIBER, LAURA, M. Patti, ESPOSITO, Simone, DIOLAITI, EMILIANO, ARCIDIACONO, CARMELO, R. C. Butler, P. Ciliegi, PUGLISI, Alfio Timothy, Oberti, Sylvain, S. Esposito, AGAPITO, GUIDO, Feautrier, Philippe, LOMBINI, MATTEO, I. Foppiani, Butler, R. C., G. Agapito, L. Schreiber, A. Puglisi, BREGOLI, Giovanni, F. Cortecchia, CORTECCHIA, Fausto, P. Feautrier, G. Bregoli, CILIEGI, Paolo, M. Lombini, C. Arcidiacono, E. Diolaiti, Patti, Mauro   +33 more
core   +1 more source

Wavefront sensing over a 20-arcmin field in the ULTIMATE-Subaru Ground Layer Adaptive Optics system

, 2022
The ULTIMATE Ground Layer Adaptive Optics (GLAO) system is part of ULTIMATE-Subaru, the next generation facility instrumentation project at the Subaru telescope in Hawaii.
Rigaut, Francois, Noelia Martínez Rey, Travouillon, Tony, Bernard, Julien Tom, Kruse, Andrew, David Chandler, Ramasundara, Wasantha, Vaughn, Israel, Yosuke Minowa, Wasantha Ramasundara, Céline d'Orgeville, Herrald, Nicholas, D'Orgeville, Celine, Koki Terao, Yoshito . Ono, Martinez, Noelia, Terao, Koki, Minowa, Yosuke, Yoko Tanaka, Ono, Yoshito, Andrew W. Kruse, Julien Tom Bernard, Chandler, David, Tony Travouillon, Tanaka, Yoko, Haynes, Dionne, Nicholas Herrald, Dionne Haynes, Israel J. Vaughn, François Rigaut   +29 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source