Results 81 to 90 of about 117,696 (296)

Correction of distortion for optimal image stacking in Wide Field Adaptive Optics: Application to GeMS data

, 2016
The advent of Wide Field Adaptive Optics (WFAO) systems marks the beginning of a new era in high spatial resolution imaging. The newly commissioned Gemini South Multi-Conjugate Adaptive Optics System (GeMS) combined with the infrared camera Gemini South ...
Andersen, M., Bernard, A., Bounissou, S., Fusco, T., Mugnier, L. M., Neichel, B., Plana, H., Samal, M., Zavagno, A.   +8 more
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A Comprehensive Review of Machine Learning Applications in Laser Optics

IEEE Photonics Journal
Machine learning (ML) has emerged as a transformative tool in laser-based optics, driving advancements in both fundamental research and industrial applications.
Saadman Yasar, Murat Yuksel
doaj   +1 more source

End to end numerical simulations of the MAORY multiconjugate adaptive optics system

, 2014
MAORY is the adaptive optics module of the E-ELT that will feed the MICADO imaging camera through a gravity invariant exit port. MAORY has been foreseen to implement MCAO correction through three high order deformable mirrors driven by the reference ...
Arcidiacono, Carmelo, Bregoli, Giovanni, Butler, R. C., Ciliegi, Paolo, Cosentino, Giuseppe, Diolaiti, Emiliano, Foppiani, Italo, Lombini, Matteo, Schreiber, Laura   +8 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Swimming with ShARCS: Comparison of On-sky Sensitivity With Model Predictions for ShaneAO on the Lick Observatory 3-meter Telescope

, 2014
The Lick Observatory's Shane 3-meter telescope has been upgraded with a new infrared instrument (ShARCS - Shane Adaptive optics infraRed Camera and Spectrograph) and dual-deformable mirror adaptive optics (AO) system (ShaneAO).
Cabak, Gerald, Cowley, David, Dillon, Daren, Gates, Elinor, Gavel, Donald, Kupke, Renate, McGurk, Rosalie, Norton, Andrew, Peck, Michael, Peck, Michael, Ratliff, Christopher, Reining, Marc, Rockosi, Constance, Srinath, Srikar   +13 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Simulation of Coherent Beam Propagation in Laboratory and Numerical Experiments: A Comparison of Results

Photonics
This paper presents the results of processing and systematizing data from laboratory and numerical experiments to correct the distortions of laser radiation propagating through a randomly inhomogeneous medium.
Feodor Kanev, Alexey Rukosuev, Ilya Galaktionov, Julia Sheldakova, Igor Veretekhin   +4 more
doaj   +1 more source

Infrared Wavefront Sensing for Adaptive Optics Assisted Galactic Center Observations with the VLT Interferometer and GRAVITY: Operation and Results

Instruments, 2020
This article describes the operation of the near-infrared wavefront sensing based Adaptive Optics (AO) system CIAO. The Coudé Infrared Adaptive Optics (CIAO) system is a central auxiliary component of the Very Large Telescope (VLT) interferometer (VLTI).
Stefan Hippler, Wolfgang Brandner, Silvia Scheithauer, Martin Kulas, Johana Panduro, Peter Bizenberger, Henry Bonnet, Casey Deen, Françoise Delplancke-Ströbele, Frank Eisenhauer, Gert Finger, Zoltan Hubert, Johann Kolb, Eric Müller, Laurent Pallanca, Julien Woillez, Gérard Zins, GRAVITY Collaboration   +17 more
doaj   +1 more source