Results 81 to 90 of about 118,114 (295)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Experimental Demonstration of Sequential Operation Approach for a Three-Sided Pyramid Wavefront Sensor

open access: yesIEEE Photonics Journal, 2016
We describe a sequential operation approach for a three-sided pyramid wavefront sensor (PWFS) based on a micromirror array with hexagonal geometry. The geometrical optics analysis and numerical simulations show that a linear relationship exists between ...
Lu Chen   +6 more
doaj   +1 more source

Lens Galaxy Properties of SBS1520+530: Insights from Keck Spectroscopy and AO Imaging [PDF]

open access: yes, 2007
We report on an investigation of the SBS 1520+530 gravitational lens system and its environment using archival HST imaging, Keck spectroscopic data, and Keck adaptive-optics imaging.
Auger M. W.   +9 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A Comprehensive Review of Machine Learning Applications in Laser Optics

open access: yesIEEE Photonics Journal
Machine learning (ML) has emerged as a transformative tool in laser-based optics, driving advancements in both fundamental research and industrial applications.
Saadman Yasar, Murat Yuksel
doaj   +1 more source

The Robo-AO-2 facility for rapid visible/near-infrared AO imaging and the demonstration of hybrid techniques [PDF]

open access: yes, 2018
We are building a next-generation laser adaptive optics system, Robo-AO-2, for the UH 2.2-m telescope that will deliver robotic, diffraction-limited observations at visible and near-infrared wavelengths in unprecedented numbers.
Baranec, Christoph   +25 more
core   +1 more source

End to end numerical simulations of the MAORY multiconjugate adaptive optics system

open access: yes, 2014
MAORY is the adaptive optics module of the E-ELT that will feed the MICADO imaging camera through a gravity invariant exit port. MAORY has been foreseen to implement MCAO correction through three high order deformable mirrors driven by the reference ...
Arcidiacono, Carmelo   +8 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Simulation of Coherent Beam Propagation in Laboratory and Numerical Experiments: A Comparison of Results

open access: yesPhotonics
This paper presents the results of processing and systematizing data from laboratory and numerical experiments to correct the distortions of laser radiation propagating through a randomly inhomogeneous medium.
Feodor Kanev   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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