Results 71 to 80 of about 256,675 (301)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Stress Testing Adaptive Social Protection Systems in the Sahel

The Sahel region of Africa faces multiple crises, which further compound structural economic and human development challenges. The Sahel is one of the world’s poorest regions and displays some of the lowest
Coudouel, Aline, Saidi, Mira, Fuselli, Silvia   +2 more
core   +1 more source

Design and Implementation of a Ku Band Waveguide Energy-Selective Device

Photonics
This paper presents a waveguide energy-selective device operating in the Ku band. By utilizing the nonlinear characteristics of PIN diodes, the device can autonomously switch its operating state according to the power level of incident signals inside the
Tongxin Liu, Chenxi Liu, Yanqing Cheng, Yanlin Xu   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Demonstration of adaptive overcurrent protection using IEC 61850 communications

, 2013
This paper contains a description of an adaptive protection scheme that has been implemented and demonstrated in a hardware in the loop simulation environment using commercially available protection hardware and IEC 61850 communications.The ...
Coffele, Federico, Kirkwood, John, Blair, Steven Macpherson, Fordyce, Bob, Booth, Campbell   +4 more
core  

Efficacy of Insecticides against Fall Armyworm, Spodoptera frugiperda (Lepidoptera, Noctuidae) in Maize

Journal of Bioresource Management, 2022
Fall armyworm (FAW), Spodoptera frugiperda (Lepidoptera: Noctuidae) is most destructive specie of genus Spodoptera for several agricultural crops. In Pakistan's Sindh province, the invasive fall armyworm Spodoptera frugiperda was first documented causing
Fawzan Masood Mian , Imtiaz Khan, Najeeb Ullah, Aqarab Husnain Gondal , Muhamad Saqib Ajmal , Muhammad Sajid Qureshi, Adnan Ihsan, Muhammad Raziq, Imran Qazi, Abdul Jabbar   +9 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Adaptive Social Protection for Pandemics in South Asia

The COVID-19 pandemic exposed significant gaps in social protection systems, especially in South Asia, where financial constraints limited support for vulnerable populations.
Sanchez-Reaza, Javier, Fatima, Tehreem
core   +2 more sources