Results 51 to 60 of about 56,790 (264)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Research on tetrahedral adaptive mesh grading refinement for intersecting faults

Gong-kuang zidonghua
Current tetrahedral adaptive mesh refinement techniques have primarily focused on the 3D reconstruction and analysis of simple stratified geological bodies. When applying adaptive mesh refinement to complex geological structures, such as those containing
CHEN Yingxian, ZHU Zhe, MA Huiru, FU Jiepeng   +3 more
doaj   +1 more source

An Adaptive h-Refinement Algorithm for Local Damage Models

Algorithms, 2009
An adaptive mesh refinement strategy is proposed for local damage models that often arise from internal state variable based continuum damage models.
Francesco Costanzo, Jonathan S. Pitt
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Efficient Adaptive Mesh Refinement Architecture on Mobile Terminals

工程科学与技术, 2014
:For the problem that mobile terminals can hardly show the three-dimensional models fast and realistically,the adaptive mesh refinement architecture adapting to mobile terminals was proposed.The general adaptive refinement template was designed to reduce
聂俊岚, 田茂春, 郭栋梁, 王艳芬   +3 more
doaj  

Self‐Supervised Anomaly Detection for Substation Equipment With Realistic Diffusion‐Based Synthesis and Adaptive Feature Refinement

IET Cyber-systems and Robotics
Industrial anomaly detection is crucial for preventing equipment failures, yet challenges persist due to limited labelled data and complex fault patterns.
Bo Xu, Jia Liu
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Adaptive Mesh Refinement for Electromagnetic Simulation

We consider problems related to initial meshing and adaptive mesh refinement for the electromagnetic simulation of various structures. The quality of the initial mesh and the performance of the adaptive refinement are of great importance for the finite element solution of the Maxwell equations, since they directly affect the accuracy and the ...
Alexey Belokrys-Fedotov, Vladimir A. Garanzha, Lennard Kamenski, Alexandr Chikitkin, Evgeniy Pesnya, Nikita Aseev, Andrey Vorobyev   +6 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source