Results 71 to 80 of about 56,790 (264)
This paper presents a verification-to-adaptivity analysis of a finite element framework for scalar and vector-valued elliptic problems that employs recovery-based a posteriori error estimation. Conforming bilinear quadrilateral (Q4) and linear triangular
J. K. Odeyemi, S. A. Odunlami
doaj +1 more source
Adaptive Grid Use in Air Quality Modeling
The predictions from air quality models are subject to many sources of uncertainty; among them, grid resolution has been viewed as one that is limited by the availability of computational resources.
Mehmet Talat Odman +1 more
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Sledgehamr: Simulating Scalar Fields with Adaptive Mesh Refinement
Understanding the nonlinear dynamics of coupled scalar fields often necessitates simulations on a 3D mesh. These simulations can be computationally expensive if a large scale separation is involved.
Malte Buschmann
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Error Estimation for Adaptive Mesh Refinement in Droplet Simulations
We present a one-dimensional shear-force-driven droplet formation model with a flux-based error estimator. The model is derived using asymptotic expansion and a front-tracking method to simulate the droplet interface.
Darsh Nathawani, Matthew Knepley
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Stratified Ocean Model With Adaptive Refinement (SOMARv2)
Numerical studies of submesoscale ocean dynamics are restricted by several challenges, including its vast range of scales, nonhydrostatic features, and strong anisotropy.
Edward Santilli +2 more
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An adaptive particle refinement (APR) algorithm has been developed for the smoothed particle hydrodynamics (SPH) method to augment the resolution of the region of interest to achieve high accuracy and simultaneously reduce the cost of computational ...
Jun Zhang +5 more
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

